Predictive Imaging Features in Renal Cell Carcinoma

NCT05042089 | Completed

• 1 other identifier: AnkaraYBU-URO-SU-03
• Study Type: observational
• Target: 92
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aimed to evaluate the role of some findings that can be detected in preoperative radiological imaging of kidney masses in predicting locally advanced disease.

Conditions

Renal Malignant Tumor

Keywords

Renal Cell Carcinoma; Tomography; Magnetic resonance imaging

Outcome Measures

Primary Outcomes (3)

• Renal capsule invasion

  Whether there was a difference between the two groups in terms of the presence of pre-operative imaging (CT and MRI) renal capsule invasion.

  1 month

• Perirenal fat tissue invasion

  Whether there was a difference between the two groups in terms of the presence of pre-operative imaging (CT and MRI) perirenal fat tissue invasion

  1 month

• Thickening of the Gerota's fascia

  Whether there was a difference between the two groups in terms of the presence of pre-operative imaging (CT and MRI) thickening of the Gerota's fascia.

  1 month

Study Arms (2)

pathological tumor stage 1-2 (pT1-2)

Stage pT1 and pT2 according to pathology results of patients who underwent partial or radical nephrectomy.

Other: No intervention will be applied.

pathological tumor stage ≥pT3a

Stage ≥pT3a according to pathology results of patients who underwent partial or radical nephrectomy.

Other: No intervention will be applied.

Interventions

No intervention will be applied. OTHER

The preoperative imaging of the participants, who were grouped according to the postoperative pathology results, will be examined.

pathological tumor stage 1-2 (pT1-2); pathological tumor stage ≥pT3a

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients aged 20-80 years who have a renal mass detected by CT or MR imaging in the urology outpatient clinic and undergo partial or radical nephrectomy.

You may qualify if:

• patients operated for kidney mass
• patients with preoperative CT or MRI imaging

You may not qualify if:

• metastatic RCC
• who had undergone surgery on the same side before kidney mass due to other urological pathologies
• who had pathology results other than RCC (oncocytoma, etc.)

Sponsors & Collaborators

• Ankara Yildirim Beyazıt University: lead

Study Sites (1)

Ankara Yildirim Beyazit University, Schhol of Medicine

Ankara, 06800, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Carcinoma, Renal Cell

Condition Hierarchy (Ancestors)

Adenocarcinoma; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Kidney Neoplasms; Urologic Neoplasms; Urogenital Neoplasms; Neoplasms by Site; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Kidney Diseases; Urologic Diseases; Male Urogenital Diseases

Study Officials

• Selman Unal

  Ankara Yildirim Beyazit University School of Medicine, Department of Urology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 4, 2021
• First Posted: September 13, 2021
• Study Start: May 1, 2021
• Primary Completion: June 1, 2021
• Study Completion: June 1, 2021
• Last Updated: September 22, 2021

Record last verified: 2021-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)