Novel Role of Exercise Timing in Obesity
FIT3 : Exercise Timing for a Novel Treatment for Obesity
FIT3 : Exercise Timing for a Novel Treatment for Obesity
Sponsor study identifier
interventional
54
1 country
1
Study Start
September 15, 2021
Actual (reported)Primary Completion
April 30, 2025
Actual (reported)Study Completion
April 30, 2025
Actual (reported)The main objective of this research project is to assess the impact of the timing of exercise on sensory perception, more specifically on taste and smell. Also, the investigators want to identify the optimal exercise timing scenario that maximizes the short-term anorexigenic effect of exercise (i.e. decrease in energy intake at the meal following the exercise session) in each group of teenagers. Hypothesis: exercise immediately before a meal (EX-\>MEAL) will be the most efficient scenario, and will show a larger impact on males individuals and people who suffer obesity. Subsequently, the investigators want to understand the impacts of exercise on lifestyle habits (i.e. sleep and sedentariness). For the realization of this research project, the investigators plan to recruit approximately 144 participants, boys and girls with normal weight/obesity, aged 12 to 17 years. Of these participants, half will be male. There are two different exercise timings (i.e. performed at 9:30 am and 11:00 am using a treadmill to test the maximal aerobic capacity) and one sedentary control condition. Participants will take part in 3 experimental visits in a random order (\~5 hours/visit at LAPS-UdeM + 24h of real-life monitoring). Appetite sensations, energy intake (i.e. total and macronutrient), activity monitoring using actigraphy, hormonal (i.e. anorexigenic and orexigenic) and chemosensory (i.e. cortical response to taste and smell stimulations) response will be monitored in the laboratory and/or remotely. This project will measure acute response in laboratory and real-life settings.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 30, 2025
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 20, 2021
Actual (reported)September 1, 2021
Actual (reported)September 15, 2021
Actual (reported)April 30, 2025
Actual (reported)April 30, 2025
Actual (reported)Energy intake at lunch
Obtained using an ad libitum meal
30 minutes
Physical activity habits outside the laboratory
Time spent in moderate-to-vigorous intensity.
24 hours
Eating habits outside the laboratory
Ambulatory monitoring of food provided that is eaten (kcal total)
24 hours
Sedentary activity habits outside the laboratory
Time spent in sedentary activities
24 hours
Chemosensory response - Taste
Within the 30 minutes devoted to chemosensory testing, prior to the meal at noon.
Circulating concentration of PYY
Within the 30 minutes devoted to chemosensory testing, prior to the meal at noon.
Chemosensory response - Smell
Within the 30 minutes devoted to chemosensory testing, prior to the meal at noon, and in the 2 hour period following meal.
Circulating concentration of GLP1
Within the 30 minutes devoted to chemosensory testing, prior to the meal at noon, and in the 2 hour period following meal.
Circulating levels of ghrelin
Within the 30 minutes devoted to chemosensory testing, prior to the meal at noon, and in the 2 hour period following meal.
A warm-up, 30 min at 70% VO2 max and a cool-down performed at 9:30 am.
A warm-up, 30 min at 70% VO2 max and a cool-down performed at 11:00 am.
Control condition. A choice of 30 minutes sedentary activities.
Treadmill (30 minutes) at 70% of maximal aerobic capacity
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Université de Montréal
Montreal, Quebec, H3C 3J7, Canada
54 participants (actual enrollment reported by the registry).
First Submitted
March 20, 2021
First Posted
Effectiveness of a Mobile Health Intervention for the Prevention of Overweight and Obesity in Adolescents
Sleep activity habits outside the laboratory
Time spent sleeping at night
24 hours
Contact the study team to confirm eligibility.
September 1, 2021
Study Start
September 15, 2021
Actual (reported)Primary Completion
April 30, 2025
Actual (reported)Study Completion
April 30, 2025
Actual (reported)Last Updated
May 26, 2026
Record last verified: 2026-05
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Source: ClinicalTrials.gov.
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