Chronic Kidney Disease Among Hypertensive Patients in Ha'il, Saudi Arabia

NCT05030480 | Completed

• 1 other identifier: H-2020-206
• Study Type: observational
• Target: 392
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic kidney disease (CKD) is defined as persistent abnormalities of kidney structure or function for more than 3 months leading to a sustained reduction in glomerular filtration rate (GFR) and/or to the occurrence of kidney damage markers, such as albuminuria. \[1\] CKD is an emerging global public health problem, having significant morbidity and mortality costs on society. It is considered as an important component of the epidemic of non-communicable diseases in developed, as well as low-income/middle-income countries. \[2\] In the Kingdom of Saudi Arabia, CKD has been established as a major health issue in recent decades due to the growing incidence and prevalence of end stage kidney disease (ESKD) among the Saudi population. The overall prevalence of CKD was 5.7% in 2010. \[3\] In 2017, there were around two million cases of CKD and 3818 deaths due to CKD in Saudi Arabia in 2017. \[4\] A recent study also reported the overall prevalence of CKD stages 3 to 5 was 4.4% among the Saudi population. \[5\] The major consequences of CKD include disease progression and, subsequently, increased risk of cardiovascular disease.

Conditions

Chronic Kidney Diseases

Outcome Measures

Primary Outcomes (1)

• PREVALANCE AND REISK FACTORS

  Prevalence of Chronic Kidney Disease and Associated Risk Factors among hypertensive non-diabetic patients

  3 MONTHS

Study Arms (2)

Chronic kidney disease

eGFR values of less than 60 mL/min/1.73 m2

Diagnostic Test: renal functions

Non-Chronic kidney disease

eGFR values more than 60 mL/min/1.73 m2

Diagnostic Test: renal functions

Interventions

renal functions DIAGNOSTIC_TEST

urea, creatinine, GFR

Chronic kidney disease; Non-Chronic kidney disease

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A cross-sectional study, enrolled 607 Saudi patients, of both sexes, registered for Ha'il University Medical Polyclinic, Ha'il city, Saudi Arabia, from October 6, 2020 to January 31, 2021. Patients eligible for inclusion in this study included those who were aged 18 years or older and were diagnosed with hypertension.

You may not qualify if:

• pregnant or breastfeeding females; history of nephrotoxic drugs use and any case with known cause of CKD other than hypertension such as diabetes mellitus, polycystic kidney disease, obstructive uropathy or autoimmune diseases.

Sponsors & Collaborators

• Zagazig University: lead

Study Sites (1)

University of Ha'il

Ha'il, 2440, Saudi Arabia

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 3 Months
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Internal Medicine- Faculty of Medicine

Study Record Dates

• First Submitted: August 20, 2021
• First Posted: September 1, 2021
• Study Start: May 11, 2020
• Primary Completion: January 18, 2021
• Study Completion: August 18, 2021
• Last Updated: September 1, 2021

Record last verified: 2021-08

Locations

SA (1)