Assessment of Quality of Life and Psychological Problems in Patients With Multiple Sclerosis

NCT05029830 | Completed

• 1 other identifier: MS
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.use QoL assessments to check whether interventions have been as effective from the patient's point of view as from the clinician's, and to determine whether further action is required . Knowledge of which factors are determinants of QoL in patients with MS would assist clinicians in choosing the most appropriate interventions. Several determinants of QoL have been identified with varying strengths of association and include both disease-related variables (disability status ,disease duration ,fatigue ,depression ,cognition , sociodemographic variables (age and sex ,level of education, and marital status . A number of these factors might be amenable to treatment intervention, which might be expected to improve QoL: fatigue , depression , and cognition
2. 2.To study effect of psychiatric comorbidity on the disease activity by using clinical, laboratory and psychiometric tools.

Conditions

Multiple Sclerosis Acute and Progressive

Outcome Measures

Primary Outcomes (1)

• Measurement affection quality of life in patient's with MS

  16 month

Secondary Outcomes (1)

• Measure psychiatric comorbidity in patients with MS

  16 month

Interventions

investigations like MRI.. COMBINATION_PRODUCT

• Multiple Sclerosis Quality of Life-54 (MSQOL-54) Can be considered as the most known disease-specific instrument for the evaluation of quality of life in patients with multiple sclerosis (MS). It was developed to combine generic quality of life aspects of the SF-36 with MS-targeted dimensions and ratings for the overall quality of life. Therefore, 18 disease-specific items were added to the original 36 items of the SF-36. The 54 items are divided into 12 multi-item and 2 single-item scales. The MSQOL-54 items are transformed linearly to 0-100 scores and final scores are obtained by averaging items within the scales

Also known as: questionnaires

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

1\) fulfillment of either of these five categories of criteria, depending on how many clinical attacks have occurred :

You may qualify if:

• fulfillment of either of these five categories of criteria, depending on how many clinical attacks have occurred
• patients aged 18 to 40 years of age.
• Males and females are included.
• All patients who received diagnosis of multiple sclerosis whether under treatment or not.

You may not qualify if:

• \) Patients age of below 18 years or over 40 years . 2) History suggestive or diagnosed collagen disease such as Bechet disease. 3) History suggestive with other general medical disease

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Samah

Asyut, Egypt

Location

Related Publications (1)

• Oh J, Vidal-Jordana A, Montalban X. Multiple sclerosis: clinical aspects. Curr Opin Neurol. 2018 Dec;31(6):752-759. doi: 10.1097/WCO.0000000000000622.

  PMID: 30300239 RESULT

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Shady safwat, lecturer

  Assiut University

  STUDY DIRECTOR

• gellan karm, lecturer

  Assiut University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident

Study Record Dates

• First Submitted: June 16, 2021
• First Posted: September 1, 2021
• Study Start: September 1, 2021
• Primary Completion: September 1, 2022
• Study Completion: October 30, 2022
• Last Updated: February 6, 2023

Record last verified: 2023-02

Locations

EG (1)