Trials Sponsors Conditions Drugs Pricing

Conditions

Cerebral Artery Stenosis Cerebrovascular Stroke

Keywords

cerebral atherosclerotic stenosisischemic stroketransient ischemic attackcerebral autoregulation

Outcome Measures

Primary Outcomes (1)

Stroke recurrence rate
Ischemic cerebrovascular recurrence (TIA or ischemic stroke) within cerebral stenotic artery supplying area diagnosed by symptoms and imaging examinations.
two years

Secondary Outcomes (6)

The index of cerebral autoregulation
within 30 days ischemic cerebrovascular events onset
ischemic cerebrovascular recurrence rate
two years
The first onset time of composite endpoint events within 2 years
two years follow-up
mRS and Barthel score
two years
The first onset time of each individual part of composite endpoint events within 2 years
two years follow-up
+1 more secondary outcomes

Study Arms (1)

sCAS patients

Investigators plan to enroll 850 patients of symptomatic cerebral atherosclerotic stenosis (sCAS) for cerebral autoregulation assessment to explore the relationship between cerebral autoregulation (CA) and stroke recurrence, determine the threshold values of CA parameter for predicting stroke recurrence associated with particular stenosis.

Diagnostic Test: Cerebral autoregulation assessment

Interventions

Cerebral autoregulation assessmentDiagnostic test

Cerebral autoregulation assessment will be conducted by specialized neurovascular ultrasound doctors during 0-3 and 10-30 days after stroke onset.The recorded data will be stored for further cerebral autoregulation analysis.

sCAS patients

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients with a diagnosis of symptomatic cerebral atherosclerotic stenosis, were recruited according to Inclusion Criteria, mostly from the First Hospital of Jilin University, and partly from other hospitals.

You may qualify if:

Age ranging from 18 to 80, both genders

Sponsors & Collaborators

The First Affiliated Hospital of Hebei North University
Othercollaborator
The Affiliated Hospital of Yanbian University
Othercollaborator

Study Sites (1)

the First Hospital of Jilin University

Changchun, Jilin, 130000, China

RECRUITING

Yi YangCONTACT

MeSH Terms

Conditions

StrokeIschemic StrokeIschemic Attack, Transient

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesBrain Ischemia

Study Officials

Yi Yang, MD, PhD
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University
STUDY CHAIR

Central Study Contacts

Yi Yang, MD, PhD

CONTACT

0086-13756661217 doctor_yangyi@163.com

Zhenni Guo, MD

CONTACT

zhen1ni2@163.com

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Target Duration: 24 Months
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Associated Dean of First Hospital of Jilin University

Study Record Dates

First Submitted

July 19, 2017

First Posted

August 31, 2021

Study Start

January 14, 2017

Actual (reported)

Primary Completion

December 24, 2025

Estimated (date passed)

Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (6)

Study Arms (1)

sCAS patients

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (6)

Study Arms (1)

sCAS patients

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations