Role of Transrectal-ultrasound in Evaluation of Azoospermia

NCT05026190 | Unknown

• 1 other identifier: infertility Azoospermia TRUS
• Study Type: interventional
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

Azoospermia is a word meaning to ejaculates with no spermatozoa without a definite underlying cause .1% of men has azoospermia, representing nearly 10 to 15% of all infertile men. The azoospermia is a major concern in our community. There is no actual epidemiological studies to estimate the actual numbers in Egypt. Azoospermia has several classifications, pre-testicular, testicular \& post-testicular cause .The semen analysis is the main investigation done for these patient .The treatment methods range from hormonal therapy to surgery or ICSI . The imaging modalities has developed greatly in the last 3 decades. That it became in several setting as a bedside test or investigation. The main modalities used in azoospermia are scrotal ultrasound, TRUS and MRI. The first TRUS was introduced 1957.

Conditions

Infertility Due to Azoospermia

Outcome Measures

Primary Outcomes (4)

• Number of patients With obstructive azoospermia

  through study completion ,within average one year.

• Number of patient with non obstructive azoospermia

  through study completion , within average one year.

• Number of patient that will respond to endoscopic treatment

  6 month duration

• Number of patients that will need sperm extraction

  9 month duration

Study Arms (1)

azoospermic patients

OTHER

Diagnostic Test: transrectal ultrasound

Interventions

transrectal ultrasound DIAGNOSTIC_TEST

we perform trus to identify the cause of azospermia and its type either obstructive or not

azoospermic patients

Eligibility Criteria

• Age: 18 Years - 60 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Adult patients with azoospermia as identified by semen analysis.
• Age from 18 years to more

You may not qualify if:

• History of operative intervention in the lower urinary tract.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Aziz N. The importance of semen analysis in the context of azoospermia. Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):35-8. doi: 10.6061/clinics/2013(sup01)05.

  PMID: 23503953 BACKGROUND

• Gudeloglu A, Parekattil SJ. Update in the evaluation of the azoospermic male. Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):27-34. doi: 10.6061/clinics/2013(sup01)04.

  PMID: 23503952 BACKGROUND

• Cocuzza M, Alvarenga C, Pagani R. The epidemiology and etiology of azoospermia. Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):15-26. doi: 10.6061/clinics/2013(sup01)03.

  PMID: 23503951 BACKGROUND

• Sihag P, Tandon A, Pal R, Jain BK, Bhatt S, Kaur S, Sinha A. Sonography in male infertility: a look beyond the obvious. J Ultrasound. 2018 Sep;21(3):265-276. doi: 10.1007/s40477-018-0294-5. Epub 2018 Mar 28.

  PMID: 29594932 BACKGROUND

Central Study Contacts

mohamed m elsharkawy

CONTACT

01065811880; mohamed.20134308@med.au.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident of urology

Study Record Dates

• First Submitted: August 4, 2021
• First Posted: August 30, 2021
• Study Start: October 5, 2021
• Primary Completion: December 5, 2022
• Study Completion: December 5, 2022
• Last Updated: August 30, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share