NCT05024604

Brief Summary

Hysteroscopic findings in women using progesterone only pills (minipills) :A Prospective cohort study.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
140

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 4, 2021

Completed
23 days until next milestone

First Posted

Study publicly available on registry

August 27, 2021

Completed
5 days until next milestone

Study Start

First participant enrolled

September 1, 2021

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 5, 2022

Completed
Last Updated

August 27, 2021

Status Verified

August 1, 2021

Enrollment Period

1 year

First QC Date

August 4, 2021

Last Update Submit

August 21, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • primary outcome

    Hysteroscopic findings in women using POPs versus those not using hormones.( cervical mucosa , endometrium )

    an average of 1 year

Secondary Outcomes (1)

  • subsidiary

    an average of 1 year

Study Arms (2)

study group

women receiving mini pills as a method of contraception with symptoms not diagnosed with us

Drug: Progesterone Only Product in Oral Dose FormOther: office hysterscopy

Control group

women attending to office hysteroscopy unit and not taking hormonal therapy

Other: office hysterscopy

Interventions

mini pills as a contraceptive method

study group

office hysteroscoy

Control groupstudy group

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsreproducative age
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

maternal health and family planning

You may qualify if:

  • study group:
  • women using POP.
  • Age: reproductive age.
  • Symptoms: abnormal uterine bleeding without an organic cause.
  • Authorization to participate in the study .
  • Control group
  • women attending to office hysteroscopy clinic
  • Age: reproductive Age
  • Contraception use : none.
  • Hormonal use: none.
  • Symptoms: abnormal uterine bleeding without an organic cause. All women in both groups would be subjected to Trans Vaginal U.S before doing hysteroscopy .

You may not qualify if:

  • study group
  • Coagulopathies
  • Any contraindications to POPs as :
  • past or current breast cancer, cirrhosis, and use of anticonvulsants
  • suspected pregnancy
  • current stroke or IHD
  • severe hypertension
  • Any contraindications to hysteroscopy as :
  • Pelvic infection
  • Pregnancy
  • Cervical cancer
  • Heavy uterine bleeding.
  • Control group --Women using any type of hormones including COCs .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Women health hospital , Assuit university

Asyut, Assuit, 71515, Egypt

RECRUITING

MeSH Terms

Interventions

Dosage Forms

Intervention Hierarchy (Ancestors)

Pharmaceutical PreparationsTechnology, PharmaceuticalInvestigative Techniques

Central Study Contacts

samuel adel gendy, master

CONTACT

atef mohamed Darwish, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Resident of Obstetrics & Gynecology

Study Record Dates

First Submitted

August 4, 2021

First Posted

August 27, 2021

Study Start

September 1, 2021

Primary Completion

September 1, 2022

Study Completion

December 5, 2022

Last Updated

August 27, 2021

Record last verified: 2021-08

Locations