Prevalence and Risk Factors for Micronutrient Deficiencies During Pregnancy in Cayenne, French Guiana

NCT05022979 | Completed

• 1 other identifier: CarMa
• Study Type: observational
• Target: 341
• Locations: 1 country
• Sites: 1

Brief Summary

Micronutrient deficiencies are frequent in pregnant women in French Guiana, a French territory in South America. Micronutrient deficiencies are more frequent in precarious women. Obesity is a frequent problem but it is also associated with micronutrient deficiency. Micronutrient deficiencies have largely been overlooked in this outermost European region and should be corrected.

Conditions

Deficiency; Diet; Pregnancy

Keywords

micronutrients; risks factors; social inequalities

Outcome Measures

Primary Outcomes (1)

• Identification of a micronutrient deficiency defined as at least one micronutrient below the lower limit.

  * urinary iodine \< 100 µg/L * blood zinc level \< 70 µg/dL * magnesium \< 0.75 mmol/L * serum retinol \< 0.70 µmol/L * erythrocyte folate \< 305 nmol/L * blood cobalamin level \< 150 pmol/L * Martial status: ferritin \< 20 µg/L; serum iron \< 15 µg/L; iron saturation coefficient of transferrin \< 16%.

  1 day

Secondary Outcomes (5)

• Sociodemographic information

  1 day

• assessment of Food diversity score

  1 day

• Obstetrical and neonatal outcomes

  1 day

• Newborn health status

  1 day

• Mother Health status

  1 day

Interventions

Observational only OTHER

The investigator collected the patient's data from the medical record and interviewed the patient to complete the nutritional questionnaire. The required biological, blood and urine samples were collected during routine blood sampling upon entry and hospitalization.

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Any woman who was pregnant (22 weeks and more), hospitalized for delivery in the Gynecological and Obstetrical Emergency Unit at Cayenne hospital could participate in the studyafter giving written informed consent.The mode of delivery or urgent/non-urgent context did not influence the eligibility for inclusion. The criteria for non-inclusion were refusal to participate in the study; being under guardianship; and having already been enrolled in the study.

You may qualify if:

• Pregnant at least 22 weeks of amenorrhea (WHO threshold for fetal viability)
• Patient hospitalized for delivery in the Gynecological and Obstetrical Emergency Unit at Cayenne hospital
• Patient's consent
• Consent of the legal representative if the patient is a minor

You may not qualify if:

• Refusalto participate in the study.
• Being under guardianship or curatorship
• Having been previously enrolled in the study

Sponsors & Collaborators

• Centre Hospitalier de Cayenne: lead

Study Sites (1)

General Hospital of Cayenne

Cayenne, 97306, French Guiana

Location

Related Publications (1)

• Duclau A, Abad F, Adenis A, Sabbah N, Leneuve M, Nacher M. Prevalence and risk factors for micronutrient deficiencies during pregnancy in Cayenne, French Guiana. Food Nutr Res. 2021 Feb 22;65. doi: 10.29219/fnr.v65.5268. eCollection 2021.

  PMID: 33776616 BACKGROUND

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 6, 2021
• First Posted: August 26, 2021
• Study Start: May 28, 2018
• Primary Completion: May 29, 2018
• Study Completion: March 31, 2019
• Last Updated: August 26, 2021

Record last verified: 2021-08

Locations

FR (1)