NCT05020717

Brief Summary

This study aim to describe hyperkalemia clinical burden and investigate the risk factors associated with the burden on HD facility level.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 17, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 25, 2021

Completed
7 days until next milestone

Study Start

First participant enrolled

September 1, 2021

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2022

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

August 25, 2021

Status Verified

August 1, 2021

Enrollment Period

11 months

First QC Date

August 17, 2021

Last Update Submit

August 24, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • To investigate the risk factors associated with hyperkalemia clinical burden on HD facility level

    Examine the association of risk factors at current status to hyperkalemia prevalence on HD facility level

    3 years

Secondary Outcomes (3)

  • To describe hyperkalemia clinical burden on HD facility level

    3 years

  • To describe sK management pattern on HD facility level

    3 years

  • To investigate the risk factors associated with crude mortality on HD facility level

    3 years

Other Outcomes (1)

  • To investigate the risk factors associated with sK > 6.0 mmol/L and sK > 6.5 mmol/L on HD facility level

    3 years

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

HD centers in China

You may qualify if:

  • For HD centers:
  • ≥ 100 patients under MHD within 3 years prior the study initiation
  • Willing to participate in the study
  • Have routine blood collection after LIDI
  • Have death records
  • For HD patients:
  • On chronic HD for ≥ 3 months

You may not qualify if:

  • Blood test on other days than those after LIDI
  • Unable to provide detailed data required by study protocol
  • Being unable to comply with study-specified procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking University People's Hospital

Beijing, Beijing Municipality, 100044, China

RECRUITING

Related Publications (2)

  • Xinju Z, Changying X, Hong L, Guisen L, Ping Z, Caili W, Zuying X, Gang X, Rong W, Rongshan L, Aili J, Hongli J, Jianxin W, Xiaoling W, Jing Y, Li Y, Pei W, Rui Z, Yunhua L, Huimin L, Jinsheng X, Menghua C, Yinhui L, Qinkai C, Zhongfei Y, Yan Z, Hong L, Wenbo H, Chen L, Zhaohui N, Lingling G, Li Z. Prevalence, practice pattern, and mortality of hyperkalemia in Chinese patients undergoing hemodialysis in the visualize HD study. Sci Rep. 2025 Jul 1;15(1):22405. doi: 10.1038/s41598-025-92609-1.

  • Zhao X, Zuo L. Multicentre, observational, retrospective cohort of hyperkalaemia burden at haemodialysis facility-level in China: the Visualize-HD study protocol. BMJ Open. 2023 Sep 21;13(9):e066394. doi: 10.1136/bmjopen-2022-066394.

Study Officials

  • Li Zuo

    Peking University People's Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of the Nephrology Department

Study Record Dates

First Submitted

August 17, 2021

First Posted

August 25, 2021

Study Start

September 1, 2021

Primary Completion

August 1, 2022

Study Completion

December 1, 2022

Last Updated

August 25, 2021

Record last verified: 2021-08

Locations