Protective Effect of Electroacupuncture on Lung in Patients Undergoing General Anesthesia

NCT05019079 | Unknown

• 1 other identifier: LDing
• Study Type: interventional
• Target: 72
• Locations: 0 countries
• Sites: N/A

Brief Summary

Objective to investigate the protective effect of preoperative electroacupuncture on lung function in patients with mechanical ventilation for more than 2 hours under general anesthesia

Conditions

Electroacupuncture; Lung Injury, Ventilator Induced

Keywords

Electroacupuncture; Lung protection; ventilator induced lung injury

Outcome Measures

Primary Outcomes (3)

• oxygenation index

  record oxygenation index

  Before anesthesia

• oxygenation index

  record oxygenation index

  2 hours after tracheal intubation

• oxygenation index

  record oxygenation index

  5 minutes after tracheal intubation removal

Secondary Outcomes (19)

• Postoperative comfort score

  during anesthesia recovery period

• sedation score (Ramsay)

  during anesthesia recovery period

• restfulness score (DRS)

  during anesthesia recovery period

• visual analogue scale (VAS)

  during anesthesia recovery period

• Length of stay

  1 week after discharge, the patient's length of stay will be recorded through medical record system

Study Arms (2)

electroacupuncture group

EXPERIMENTAL

In the electroacupuncture group, acupoints of Lieque (+), Chize (-), Sanyinjiao (-), Zusanli (+), Tanzhong (+) and Yutang (-) will be selected for electrical stimulation. Density wave will be selected, and the current intensity should be tolerated by the patients. Conventional anesthesia operation could be started after the connection of electroacupuncture, and acupuncture point stimulation was stopped 30min later.

Other: electroacupuncture

control group

NO INTERVENTION

The patient underwent routine anesthesia without acupuncture treatment

Interventions

electroacupuncture OTHER

In the electroacupuncture group, acupoints of Lieque (+), Chize (-), Sanyinjiao (-), Zusanli (+), Tanzhong (+) and Yutang (-) will be selected for electrical stimulation. Density wave will be selected, and the current intensity should be tolerated by the patients. Conventional anesthesia operation could be started after the connection of electroacupuncture, and acupuncture point stimulation will be stopped 30min later.

electroacupuncture group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients undergoing general anesthesia in our hospital;
• Ages 18-60;
• American Society of Anesthesiologists (ASA) grade ⅱ \~ III , no severe respiratory, circulation, liver, kidney, coagulation function abnormalities;
• Expected duration of operation \>2h;
• Surgical grade 2-4;
• No serious lung infection and lung disease;
• Body mass index (BMI) 18\~30 kg/m2; There are no contraindications for electroacupuncture stimulation.

You may not qualify if:

• Patients with severe circulatory or other system dysfunction;
• Patients with pulmonary and one-lung ventilation;
• Unwilling to cooperate with the patient;
• Patients with low compliance.

Sponsors & Collaborators

• Lingling Ding: lead

MeSH Terms

Conditions

Ventilator-Induced Lung Injury

Interventions

Electroacupuncture

Condition Hierarchy (Ancestors)

Lung Injury; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Combined Modality Therapy; Therapeutics; Acupuncture Therapy; Complementary Therapies; Electric Stimulation Therapy; Physical Therapy Modalities; Rehabilitation; Transcutaneous Electric Nerve Stimulation; Analgesia; Anesthesia and Analgesia; Anesthesia

Central Study Contacts

Lingling Ding, Doctor

CONTACT

+86 010 52176647; dinglingling301@126.com

Jiaqi Ning, bachelor

CONTACT

+86 010 52176647; ningjiaqi95@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 25, 2021
• First Posted: August 24, 2021
• Study Start: September 1, 2021
• Primary Completion: September 1, 2022
• Study Completion: September 1, 2023
• Last Updated: August 24, 2021

Record last verified: 2021-08