Early and Late Complications of COVID-19

NCT05018052 | Unknown

• 1 other identifier: Stop-Covid/1/2021
• Study Type: observational
• Target: 1,900
• Locations: 1 country
• Sites: 1

Brief Summary

Coronavirus disease 2019 (COVID-19) is a serious respiratory disease that results from infection with a newly discovered coronavirus (SARS-COV-2). Unfortunately, COVID-19 is not only a short-term infection. Patients (pts) recovering from SARS-COV2 infection complain of persisting symptoms including: fatigue, diffuse myalgia and weakness, which may lead to chronic fatigue syndrome and as well as many other complications. The vast majority of COVID-19 patients remaining in isolation/quarantine, due to the mild course of the disease, do not require hospitalization. In this group of patients, the course of COVID-19 is very different - from asymptomatic patients to very severe and long lasting symptoms also with a decrease in saturation. There are many studies describing the course and complications of patients hospitalized due to COVID-19. There is little published data on how non-hospitalized patients get sick and what are the early and late complications of SARS-CoV-2 infection. In addition, many patients remain ill even many months after COVID-19, entering what is known as LONG-COVID. Therefore, the STOP-COVID Registry was established. The purpose of the Registry is to assess the course of COVID-19 infection, early and late cardiovascular complications of COVID-19 in patients with and without hospitalization. In addition, the purpose of the STOP-COVID Registry is to assess the incidence of LONG-COVID with all other complications and to identify predictive factors.

Conditions

Covid19; LONG-COVID

Keywords

Covid19; Covid complications; Long-Covid; Chronic Fatigue Syndrome

Outcome Measures

Primary Outcomes (3)

• Early and Late COVID-19 cardio-vascular complications

  Early and Late COVID-19 cardio-vascular complications

  5 years

• Predictors of Long-Covid Cardio-Vascular complications

  Predictors of Long-Covid Cardio-Vascular complications

  5 years

• SCORE - algorithm to help to predict the highest risk of Long-Covid complications

  SCORE - algorithm to help to predict the highest risk of Long-Covid complications

  5 years

Secondary Outcomes (3)

• Detailed patients' characteristics and differences in those with and without Long-Covid complications

  5 years

• Definition and characteristics of the early and Late COVID-19 complications

  5 years

• Comparison of complications and Long-Covid depending on the severity of the course of COVID-19 COVID-19, comorbidities

  5 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients 18 years and older diagnosed with COVID-19, after full recovery (resolution of clinical symptoms, minimum 14 days after last symptoms), with and without hospitalization .

You may qualify if:

• Patients after COVID-19, 18 years and older

You may not qualify if:

• None

Sponsors & Collaborators

• Michal Chudzik: lead

Study Sites (1)

Medical Center, Saint Family Hospital

Lodz, 90-302, Poland

Location

Related Publications (2)

• Babicki M, Kapusta J, Kolat D, Kaluzinska-Kolat Z, Mastalerz-Migas A, Jankowski P, Chudzik M. Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry. BMC Infect Dis. 2025 Apr 9;25(1):489. doi: 10.1186/s12879-025-10774-0.

  PMID: 40205590 DERIVED

• Kapusta J, Chudzik M, Kaluzinska-Kolat Z, Kolat D, Burzynska M, Jankowski P, Babicki M. Do selected lifestyle parameters affect the severity and symptoms of COVID-19 among elderly patients? The retrospective evaluation of individuals from the STOP-COVID registry of the PoLoCOV study. J Infect Public Health. 2023 Jan;16(1):143-153. doi: 10.1016/j.jiph.2022.12.008. Epub 2022 Dec 12.

  PMID: 36521330 DERIVED

Related Links

• Related Info

MeSH Terms

Conditions

COVID-19; Post-Acute COVID-19 Syndrome; Fatigue Syndrome, Chronic

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Encephalomyelitis; Neuroinflammatory Diseases; Nervous System Diseases; Neuromuscular Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Medical Doctor, Cardiologist, Medical Director Ambulatory Clinic

Study Record Dates

• First Submitted: August 23, 2021
• First Posted: August 24, 2021
• Study Start: May 29, 2020
• Primary Completion: September 30, 2022
• Study Completion: September 30, 2022
• Last Updated: August 24, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)