NCT05013021

Brief Summary

The present study aims to analyse first, the acute effects generated by a single bout of Sprint Interval Training (SIT) and, secondly, the effects of a long-term intervention on sedentary participants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 10, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

August 19, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

September 27, 2021

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 8, 2023

Completed
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 29, 2023

Completed
Last Updated

July 19, 2023

Status Verified

June 1, 2022

Enrollment Period

1.4 years

First QC Date

August 10, 2021

Last Update Submit

July 18, 2023

Conditions

Sedentary Behavior

Keywords

Sprint Interval TrainingVO2maxacute fatiguechronic fatigueforce-velocity profile

Outcome Measures

Primary Outcomes (1)

  • oxygen uptake (VO2max) - ml/min/kg

    consumption oxygen uptake (VO2max) measured on a cycle ergometer The main objective is to determine at which time frame of sprint interval training blocks, the endurance performance (VO2max) is best.

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

Secondary Outcomes (9)

  • Maximum power (W)

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  • Maximum theoretical force (N.m)

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  • Maximum theoretical speed (m/s)

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  • Maximum isometric force (N.m)

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  • heart rate variability (HRV)

    At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  • +4 more secondary outcomes

Study Arms (1)

Sedentary participants

OTHER

Series of measures placed throughout the time-course (before, after the 1st , the 2nd and the 3rd block of SIT). These measurements consist of physiological measurements (VO2max), neuromuscular capacities (force-speed profile), autonomic nervous system responses (heart rate variability) and blood markers (lactate, CK, cytokinases, µRNA).

Other: Sprint Interval Training

Interventions

Sprint Interval TrainingOTHER

The Sprint Interval Training (SIT) training consists of 3 successive blocks of 5 training sessions each. The sessions are 24 to 48 hours apart. . One block lasts two weeks. After the end of one block, the following block begins the day after. The Sprint Interval Training lasts 6 weeks. Each session consists of a series of sprints, the number of which varies from 8 to 14. Thus a session will last from 30 to 45 min approximately So, the time frame of this study is Baseline, Block 1, Block 2 and Block 3 (Not in day or week or month)

Sedentary participants

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • untrained healthy (less than 2 hours of sport per week)
  • free from muscular, bone or joint injuries
  • free from neurologic disease

You may not qualify if:

  • taking neuroactive substances that can alter corticospinal excitability
  • Heart or respiratory failure.
  • Subjects who have taken corticosteroids within 3 months (inhalation, infiltration or history of corticosteroid therapy).
  • Pregnant woman
  • Subject under guardianship

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Saint-Etienne

Saint-Etienne, 42055, France

Location

Related Publications (1)

  • Lloria-Varella J, Koral J, Ravel A, Murias JM, Feasson L, Busso T. Cardiorespiratory and Neuromuscular Improvements Plateau after 2 wk of Sprint Interval Training in Sedentary Individuals. Med Sci Sports Exerc. 2024 May 1;56(5):876-884. doi: 10.1249/MSS.0000000000003357. Epub 2023 Dec 13.

    PMID: 38109197DERIVED

MeSH Terms

Conditions

Sedentary Behavior

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Leonard FEASSON, MD-PhD

    Centre Hospitalier Universitaire de Saint Etienne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: Sedentary participants
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 10, 2021

First Posted

August 19, 2021

Study Start

September 27, 2021

Primary Completion

March 8, 2023

Study Completion

March 29, 2023

Last Updated

July 19, 2023

Record last verified: 2022-06

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)