NCT05012007

Brief Summary

This is a randomized controlled trial that will evaluate the effectiveness of different reminder modalities for a population-based mailed FIT program at the VA Puget Sound among average risk Veterans who are due for annual colorectal cancer (CRC) screening.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,653

participants targeted

Target at P75+ for not_applicable colorectal-cancer

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable colorectal-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 22, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

August 1, 2021

Completed
18 days until next milestone

First Posted

Study publicly available on registry

August 19, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 26, 2022

Completed
Last Updated

May 4, 2022

Status Verified

May 1, 2022

Enrollment Period

7 months

First QC Date

June 22, 2021

Last Update Submit

May 2, 2022

Conditions

Keywords

Cancer screeningAdherence

Outcome Measures

Primary Outcomes (1)

  • Percentage of returned FIT Kits

    the return rate at three months post randomization

    three months post randomization

Secondary Outcomes (1)

  • Percentage of returned FIT Kits

    six months post randomization

Other Outcomes (1)

  • Interim analysis

    At 50% (n = 1327) of estimated sample size

Study Arms (3)

Control arm: No Reminder

NO INTERVENTION

Usual care

Automated phone reminder

EXPERIMENTAL

Standard reminder via phone (audiocare)

Other: Reminder Phone

Text reminder

EXPERIMENTAL

Standard reminder via text (VEText)

Other: Reminder Text

Interventions

Standard reminder via phone (audiocare)

Automated phone reminder

reminder via text (VEText)

Text reminder

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Veterans assigned to a primary care provider at the VA Puget Sound as of January 1, 2021
  • At least 1 year of prior data available (evidence of at least one outpatient visit).
  • Due for annual CRC screening

You may not qualify if:

  • Not scheduled for either a screening or diagnostic colonoscopy within the following 12 weeks from assessment.
  • No indication of current receipt of hospice care or record of recent death in the administrative data.
  • No personal history of CRC or history of prior colectomy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Puget Sound Health Care System

Seattle, Washington, 98108, United States

Location

Related Publications (1)

  • Deeds S, Schuttner L, Wheat C, Gunnink E, Geyer J, Beste L, Chen A, Dominitz JA, Nelson K, Reddy A. Automated Reminders Enhance Mailed Fecal Immunochemical Test Completion Among Veterans: a Randomized Controlled Trial. J Gen Intern Med. 2024 Jan;39(1):113-119. doi: 10.1007/s11606-023-08409-8. Epub 2023 Sep 20.

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Study Officials

  • Ashok Reddy, MD

    VA Puget Sound Health Care System

    PRINCIPAL INVESTIGATOR
  • Stefanie Deeds, MD

    VA Puget Sound Health Care System

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Staff Physician

Study Record Dates

First Submitted

June 22, 2021

First Posted

August 19, 2021

Study Start

August 1, 2021

Primary Completion

March 1, 2022

Study Completion

April 26, 2022

Last Updated

May 4, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations