Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
FRESH
1 other identifier
interventional
162
1 country
1
Brief Summary
This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2021
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 12, 2021
CompletedFirst Posted
Study publicly available on registry
August 18, 2021
CompletedStudy Start
First participant enrolled
August 25, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 15, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
June 15, 2023
CompletedMarch 23, 2023
March 1, 2023
1.7 years
August 12, 2021
March 21, 2023
Conditions
Outcome Measures
Primary Outcomes (6)
2-Back Task (Change)
Change in Accuracy over time
during fatigue manipulation
2-Back Task (Change)
Change in Reaction Time over time
during fatigue manipulation
Fatigue State Questionnaire
Fatigue State Questionnaire Score
up to 5 mins after fatigue manipulation
Electrocardiograph (Change)
Change in Heart Rate Variability over time
during fatigue manipulation
Electrodermal Activity (Change)
Change in Skin Conductance Level over time
during fatigue manipulation
Electrodermal Activity (Change)
Change in Skin Conductance Response over time
during fatigue manipulation
Study Arms (1)
Fatigue Manipulation
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- Singapore-based
- Non-clinical
- years
You may not qualify if:
- Individuals with hearing difficulties or failing to meet the minimal threshold for normal hearing
- Individuals with a history of ear, developmental, neurological, or psychiatric disorder
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Nanyang Technological Universitylead
- National Research Foundation, Singaporecollaborator
- Ministry of National Development, Singaporecollaborator
- Housing and Development Board, Singaporecollaborator
Study Sites (1)
Cultural Science Innovations, Nanyang Technological University
Singapore, 639798, Singapore
Related Publications (1)
Lee KFA, Gan WS, Christopoulos G. Biomarker-Informed Machine Learning Model of Cognitive Fatigue from a Heart Rate Response Perspective. Sensors (Basel). 2021 Jun 2;21(11):3843. doi: 10.3390/s21113843.
PMID: 34199416BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
August 12, 2021
First Posted
August 18, 2021
Study Start
August 25, 2021
Primary Completion
May 15, 2023
Study Completion
June 15, 2023
Last Updated
March 23, 2023
Record last verified: 2023-03
Data Sharing
- IPD Sharing
- Will not share