NCT05007405

Brief Summary

Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are :

  • To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome
  • To compare OAI of urinary origin with those with another origin

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
81

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 12, 2021

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

August 11, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 16, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

September 19, 2024

Status Verified

August 1, 2021

Enrollment Period

11 months

First QC Date

August 11, 2021

Last Update Submit

September 3, 2024

Conditions

Articular Disease

Keywords

Osteoarticular infectionBacteriaUrinary tract infections

Outcome Measures

Primary Outcomes (1)

  • Identification of the spectrum of osteoarticular infections in adult, in a rheumatology department

    The purpose of this database is to describe the spectrum of osteoarticular infections in adults, non-tuberculosis germs, in a rheumatology department of a CHG during the 2010s

    Through study completion, an average of 1 year

Secondary Outcomes (1)

  • Prevalence of urinary origin in osteoarticular infections in adults, compared with other origins

    Through study completion, an average of 1 year

Study Arms (1)

Osteoarticular infections

Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Other: Groups/Cohortes

Interventions

Groups/CohortesOTHER

Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Also known as: Osteoarticular infections
Osteoarticular infections

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

You may qualify if:

  • Subject aged 18 years and over at the time of diagnosis
  • Osteoarticular infection (septic arthritis, spondylodiscitis), by a bacterium or a fungus, proven by a bacteriological sample in situ or in the blood by positive blood culture (with an unequivocal clinical, biological and imaging feature),
  • Diagnosed between 01/01/2010 and 12/31/2020 (11 years)
  • Hospitalization in the rheumatology department of CH René Dubos, Pontoise

You may not qualify if:

  • Bacterial infection due to the following germs: mycobacteria, brucella, Borrelia
  • Early infection on joint prosthesis
  • Peripheral osteomyelitis
  • Osteoarticular infection without bacteriological proof

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Rheumatology, Hospital René Dubos, Pontoise

Pontoise, 95300, France

Location

Related Publications (2)

  • Ross JJ. Septic Arthritis of Native Joints. Infect Dis Clin North Am. 2017 Jun;31(2):203-218. doi: 10.1016/j.idc.2017.01.001. Epub 2017 Mar 30.

    PMID: 28366221BACKGROUND

  • Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer AF, Schmitt SK, Hendershot EF, Holtom PD, Huddleston PM 3rd, Petermann GW, Osmon DR, Infectious Diseases Society of America. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015 Sep 15;61(6):e26-46. doi: 10.1093/cid/civ482. Epub 2015 Jul 29.

    PMID: 26229122BACKGROUND

MeSH Terms

Conditions

Joint DiseasesUrinary Tract Infections

Interventions

Population Groups

Condition Hierarchy (Ancestors)

Musculoskeletal DiseasesInfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

DemographyPopulation Characteristics

Study Officials

  • Edouard Pertuiset, Dr

    Hôpital NOVO

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 11, 2021

First Posted

August 16, 2021

Study Start

February 12, 2021

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

September 19, 2024

Record last verified: 2021-08

Locations

FR(1)