Neutrophil to Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR) as an Inflammatory Markers to Predict Length of Hospital Stay After Total Laparoscopic Hysterectomy (TLH) for Benign Indications

NCT05003297 | Completed

• 1 other identifier: GaziosmanpasaTREHd
• Study Type: observational
• Target: 150
• Locations: 0 countries
• Sites: N/A

Brief Summary

Due to short hospital stay, rapid return to work, less pain, and good cosmetic results, laparoscopic hysterectomy ( LH) has substantially increased the era of hysterectomy procedures especially for the last two decades. The main reason for this is probably that LH leads to fewer inflammatory responses when compared to open abdominal hysterectomy. Although the inflammatory response is supposed to be lower with total laparoscopic hysteroscopy (TLH), unpredictable inflammatory response as a result of the operation has been still unenlightened and it can be associated with hospital stay.

Conditions

Inflammation; Hospital Stay; Total Laparoscopic Hysterectomy

Outcome Measures

Primary Outcomes (2)

• Postoperative NLR values compared in patients who were hospitalized for more than 3 days and equal to or less than 3 days.

  NLR was calculated by dividing the absolute number of neutrophil to the absolute number of lymphocytes.

  4 years

• Postoperative PLR values compared in patients who were hospitalized for more than 3 days and equal to or less than 3 days.

  PLR were calculated by dividing the absolute number of platelets to the absolute number of lymphocytes.

  4 years

Study Arms (2)

patients whom were hospitalized for 3 days or less

Other: hemogram inflammatory parameters

patients hospitalized for more than 3 days

Other: hemogram inflammatory parameters

Interventions

hemogram inflammatory parameters OTHER

Neutrophil to Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR)

patients hospitalized for more than 3 days; patients whom were hospitalized for 3 days or less

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients whom have undergone TLH without any postoperative surgical complications

You may qualify if:

• Patients whom have undergone TLH

You may not qualify if:

• Ureter injury
• Bladder injury,
• Bowel injury,
• Superficial inferior mesenteric artery injury
• Vaginal cuff hematoma
• Vaginal cuff dehiscence
• Endometriosis
• Endometrial cancer
• Cervical cancer
• Chronic lymphocytic leukemia
• Behçet disease
• Electrolyte imbalance
• Thyroid disease
• Using anti-inflammatory medications
• Having severe intraabdominal adhesions

Sponsors & Collaborators

• Gaziosmanpasa Research and Education Hospital: lead

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: August 1, 2021
• First Posted: August 12, 2021
• Study Start: January 1, 2014
• Primary Completion: November 30, 2018
• Study Completion: December 30, 2018
• Last Updated: August 25, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, CSR, ANALYTIC CODE
• Time Frame: The data is available now