NCT04999930

Brief Summary

COPD patient on Tiotropium Respimart divided into two group, Group A given aerochamber and Group B without aerochamber enroll in the study for total 18 week .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable chronic-obstructive-pulmonary-disease

Timeline
Completed

Started Jan 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 10, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 18, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

August 11, 2021

Completed
Last Updated

August 18, 2021

Status Verified

August 1, 2021

Enrollment Period

1.1 years

First QC Date

June 18, 2021

Last Update Submit

August 11, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • To compare the frequency of exacerbation (number of events ) and hospital admission (number of admissions) using tiotropium with and without aerochamber

    Comparing frequency of exacerbation (number of events ) and hospital admission (number of admissions) in both groups

    18 weeks

Secondary Outcomes (4)

  • Change of FEV1 (%) between the treatment group

    18 weeks

  • Types of inhaler technique error between the group

    18 weeks

  • To assess quality of life (SGRQ questionaire)

    18 weeks

  • To assess patients satisfaction and preference, attitudes, and perceptions about their inhalers using questionnaire

    18 weeks

Study Arms (2)

Group A

EXPERIMENTAL

with aerochamber

Device: Aerochamber

Group B

EXPERIMENTAL

without aerochamber

Device: Aerochamber

Interventions

efficacy and patients satisfaction

Also known as: Tiotropium respimart
Group AGroup B

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • COPD patients under Respiratory clinic UKM follow up
  • Patients who are with stable COPD (no exacerbation past 2 months)
  • Age same and more than 40-year-old
  • Patient able to perform inhaler medication
  • Patient able to perform technically acceptable pulmonary function test

You may not qualify if:

  • Drug hypersensitivity
  • Bronchial Asthma
  • Significant disease that may influence patient's ability to participate in the study.
  • Unable to provide signed informed consent
  • Mental condition rendering the subject unable to understand the nature, scope and the possible consequences of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National University of Malaysia

Cheras, Kuala Lumpur, 50600, Malaysia

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor Doctor

Study Record Dates

First Submitted

June 18, 2021

First Posted

August 11, 2021

Study Start

January 10, 2020

Primary Completion

February 28, 2021

Study Completion

February 28, 2021

Last Updated

August 18, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations