The Effect of Liposuction on Menses: a Retrospective Study
1 other identifier
interventional
516
0 countries
N/A
Brief Summary
The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for early_phase_1
Started Jun 2016
Longer than P75 for early_phase_1
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 14, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 12, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
March 12, 2021
CompletedFirst Submitted
Initial submission to the registry
July 22, 2021
CompletedFirst Posted
Study publicly available on registry
August 2, 2021
CompletedAugust 2, 2021
July 1, 2021
4.7 years
July 22, 2021
July 22, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
menstrual irregularity
to detect any change in the menses during the following 3 months, post surgery
three months
Study Arms (2)
liposuction group
EXPERIMENTALOther plastic surgery group
PLACEBO COMPARATORInterventions
A small, inconspicuous incision was made in the liposuction group to dislodge fat out of the body.
Other plastic surgery like blepharoplasty or keloid excision.
Eligibility Criteria
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Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- early phase 1
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
July 22, 2021
First Posted
August 2, 2021
Study Start
June 14, 2016
Primary Completion
March 12, 2021
Study Completion
March 12, 2021
Last Updated
August 2, 2021
Record last verified: 2021-07
Data Sharing
- IPD Sharing
- Will not share