Prospective Clinical Study of Excessive Lateral Pressure Syndrome
1 other identifier
observational
200
0 countries
N/A
Brief Summary
The study of July 2021 to July 2022 to undergraduate course to see a doctor and accept the lateral retinaculum capsule of external release the prospectie study of 100 patients with follow-up, compared with preoperative and postoperative imaging data, clinical manifestations, signs, etc., to evaluate the surgical effect, at the same time of resection specimens for pathology and genetics research,To investigate the pathogenesis of lateral patella compression syndrome.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2021
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 27, 2021
CompletedFirst Posted
Study publicly available on registry
July 30, 2021
CompletedStudy Start
First participant enrolled
September 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2024
CompletedJuly 30, 2021
July 1, 2021
10 months
June 27, 2021
July 25, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change of lesions
The improvement of cartilage injury of patellofemoral joint and tibiofemoral joint. Two senior surgeons read the MRI separately, recording the status of lesion area. The lesion area was compared before and after surgery. Using Outerbridge Classification to evaluate the severity of cartilage injury.
2years
Secondary Outcomes (2)
Pain severity change
2years
Clinical symptom change
2years
Study Arms (2)
observation group
People suffered from excessive lateral pressure syndrome with extracapsular release of lateral retinaculum.
control group
People suffered from excessive lateral pressure syndrome with conservative treatment
Interventions
A new kind of surgery releases the lateral retinaculum from outside the knee capsular, maintaining the structure of the knee capsular.
Eligibility Criteria
Young and middle-aged sports active people
You may qualify if:
- Age \<40.
- Normal strength line of lower limbs: no valgus or varus feet (HKA \<±5°)
You may not qualify if:
- Combined patella dislocation and medial retinacular injury.
- Have a history of knee surgery, knee injury and fracture.
- Complicated cruciate ligament injury and medial and lateral collateral ligament injury.
- Combined knee osteoarthritis.
- Complicated with rheumatism, rheumatoid arthritis and other types of arthritis
- Patellar bisection, trochlear dysplasia
- Gouty arthritis and hyperuricemia of the knee
- Complicated meniscus injury of degree III or above
- Incorporating lateral discoid meniscus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Peking University Third Hospitallead
- Weihai Wendeng District Central Hospitalcollaborator
- Inner Mongolia Autonomous Region Hospitalcollaborator
- Beijing Delconi Orthopaedic Hospitalcollaborator
Biospecimen
lateral retinaculum of the knee
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 27, 2021
First Posted
July 30, 2021
Study Start
September 1, 2021
Primary Completion
July 1, 2022
Study Completion
July 1, 2024
Last Updated
July 30, 2021
Record last verified: 2021-07
Data Sharing
- IPD Sharing
- Will not share