NCT04980742

Brief Summary

Based on a review of about 10,000 patients undergoing cardiac surgery under CPB in West China Hospital of Sichuan University and the Second Affiliated Hospital of Zhejiang University, we try to evalute the effect of blood transfusion on outcomes in cardiac surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
3,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2017

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

August 23, 2020

Completed
11 months until next milestone

First Posted

Study publicly available on registry

July 28, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

July 28, 2021

Status Verified

August 1, 2020

Enrollment Period

4.5 years

First QC Date

August 23, 2020

Last Update Submit

July 19, 2021

Conditions

Post-cardiac SurgeryBlood Transfusion ComplicationPrognosis

Outcome Measures

Primary Outcomes (1)

  • mortality

    all-cause death

    28 days after surgery

Interventions

acute normovolemic hemodilutionPROCEDURE

acute normovolemic hemodilution

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The patients in the west China hospital of sichuan university (July 01, 2011, solstice during June 30, 2017) and the second affiliated hospital of zhejiang university (September 01, 2013, solstice, June 30, 2017) have cardiac surgery under Cardiopulmonary bypass (CPB)

You may qualify if:

  • The patients in the west China hospital of sichuan university (July 01, 2011, solstice during June 30, 2017) and the second affiliated hospital of zhejiang university (September 01, 2013, solstice, June 30, 2017) have cardiac surgery under Cardiopulmonary bypass (CPB)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ANH

Hangzhou, China

RECRUITING

MeSH Terms

Conditions

Transfusion Reaction

Condition Hierarchy (Ancestors)

Hematologic DiseasesHemic and Lymphatic DiseasesImmune System Diseases

Study Officials

  • Min Yan, doctor

    The Second Affiliated Hospital of Zhejiang University Medical College

    STUDY CHAIR

Central Study Contacts

Min Yan, doctor

CONTACT

+86-571-87783716zryanmin@zju.edu.cn

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 23, 2020

First Posted

July 28, 2021

Study Start

July 1, 2017

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

July 28, 2021

Record last verified: 2020-08

Locations

CN(1)