Acute Kidney Injury Among COVID-19 Positive Patients
AKI-COVID-19
1 other identifier
observational
649
1 country
2
Brief Summary
In Kuwait, the total number of COVID-19 confirmed cases exceeds 5000 patients. Risk factors of possible risk factors of confirmed COVID-19 infection that developed major organ dysfunction are not yet identified among patients in Kuwait. we aimed to describe the clinical characteristics of hospitalized symptomatic COVID-19 positive patients, assess possible risk factors of confirmed COVID-19 infection who developed major organ dysfunction, determine risk factors for renal dysfunction and their outcome and assess the response of critically ill patients to different therapeutic modalities.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2020
Shorter than P25 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2020
CompletedFirst Submitted
Initial submission to the registry
July 22, 2021
CompletedFirst Posted
Study publicly available on registry
July 28, 2021
CompletedJuly 28, 2021
March 1, 2020
6 months
July 22, 2021
July 26, 2021
Conditions
Outcome Measures
Primary Outcomes (2)
patient survival
Patients who survived after 30 days.
30 days
Kidney survival
Patients who have stable basal kidney function.
30 days
Study Arms (2)
Group 1
patients with stable renal function.
Group 2
Patients who developed AKI.
Interventions
Covid-19 patients with stable kidney function will represent group 1.
Covid-19 patients with unstable kidney function will represent group 2.
Eligibility Criteria
649 COVID-19 positive patients were identified. Sixty-three were isolated at home and 586 cases needed hospital admission during the period between the 1st week of March till the end of August 2020. Among the hospitalized cases, 258 needed ICU care while 328 were managed in the COVID general wards. We compared patients with stable renal function (group 1, n=319) vs. those who developed AKI (group 2, n=267). We collected the data from COVID-19 positive patients that were diagnosed in all government hospitals in Kuwait. Clinical features, details of management, and both patient and renal outcomes were recorded. We compiled patients' data from the electronic database of the isolation hospitals where COVID -19 cases were managed. Approval for the study was obtained from the ethical committee of the Kuwait Ministry of Health.
You may qualify if:
- All adult patients were included.
- Hospitalized with PCR confirmed COVID-19 infection.
- period between March to August 2020.
You may not qualify if:
- Pediatric patients Home isolated patients
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Osama Gheith
Kuwait City, AZ, 23424, Kuwait
Osama Gheith
Kuwait City, Rf, Kuwait, Kuwait
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 30 Days
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 22, 2021
First Posted
July 28, 2021
Study Start
March 1, 2020
Primary Completion
August 31, 2020
Study Completion
August 31, 2020
Last Updated
July 28, 2021
Record last verified: 2020-03