Risk Factors in Young Middle Eastern Women With Cardiovascular Disease

NCT04975503 | Completed

• 1 other identifier: IH/JCCG1-RFYW
• Study Type: observational
• Target: 627
• Locations: 1 country
• Sites: 1

Brief Summary

Cardiovascular disease continues to be the leading cause of death among women in the Middle East, including Jordan. Sex-specific data focused on cardiovascular disease have been increasing steadily, yet is not the subgroup of young women. This study focuses on classical and novel risk factors of cardiovascular disease in young women compared with older women.

Conditions

Cardiovascular Diseases; Risk Factors

Keywords

Atherosclerotic cardiovascular disease; Risk factors

Outcome Measures

Primary Outcomes (1)

• Prevalence of classical CVD risk factors

  To study the prevalence of the 4 classical risk factors (HTN, DM, smoking, and dyslipidemia) in young women (younger than 50 years of age) who have documented CVD in ambulatory and in-patient settings and compare the data with women older than 50 y of age with CVD.

  August 2021 to September 2020.

Secondary Outcomes (1)

• Prevalence of novel/emerging CVD risk factors

  August 2021 to September 2022.

Study Arms (2)

Young Women

Young women, aged 18 to 50 years, with documented atherosclerotic cardiovascular disease

Other: Observing cardiovascular risk factors

Older Women

Older women, aged \>50 years, with documented atherosclerotic cardiovascular disease

Other: Observing cardiovascular risk factors

Interventions

Observing cardiovascular risk factors OTHER

Documenting the presence or absence of CVD risk factors in each participant.

Older Women; Young Women

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Participant eligibility is based on self-representation of gender identity.
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The prevalence of the 4 classical risk factors (HTN, DM, smoking, and dyslipidemia) will be studied in young women (younger than 50 years of age, and older than 18 y of age) who have documented CVD in ambulatory and in-patient settings. This data will be compared with those from women older than 50 y of age with CVD.

You may qualify if:

• Women aged 18 y or more.
• Documented CVD (CAD stable or ACS, PCI, CABG, CVA/TIA, carotid disease, PAD).

You may not qualify if:

• Women younger than 18 years of age.
• No documented CVD.

Sponsors & Collaborators

• Jordan Collaborating Cardiology Group: lead

Study Sites (1)

Istishari Hospital

Amman, 11880, Jordan

Location

Related Publications (1)

• Hammoudeh AJ, Jallad M, Khader Y, Badaineh Y, Tabbalat RA, Zammar H, Al-Makhamreh H, Basha A, AlAtteili L, Abuhalimeh R, Fkheideh T, Ababneh A, Ababneh L, Mahmoud SA, Alhaddad IA. Atherosclerotic Cardiovascular Disease Novel and Traditional Risk Factors in Middle Eastern Young Women. The ANCORS-YW Study. Glob Heart. 2024 Jul 15;19(1):59. doi: 10.5334/gh.1341. eCollection 2024.

  PMID: 39035774 DERIVED

MeSH Terms

Conditions

Cardiovascular Diseases; Atherosclerosis

Condition Hierarchy (Ancestors)

Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Reham Nasseddin, MD

  Jordan Collaborating Cardiology Group

  STUDY DIRECTOR

• Laith N Habahbeh, MD

  Jordan Collaborating Cardiology Group

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Interventional Cardiologist, Department of cardiology, Istishari Hospital, Amman, Jordan

Study Record Dates

• First Submitted: July 14, 2021
• First Posted: July 23, 2021
• Study Start: August 22, 2021
• Primary Completion: October 30, 2023
• Study Completion: October 31, 2023
• Last Updated: January 30, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

JO (1)