Prevalence of Dementia and Delirium in Outpatient Clinics (DESTAN Trial)

NCT04973709 | Unknown

• 1 other identifier: 2020-382
• Study Type: observational
• Target: 714
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to assess the prevalence and etiologic risk factors of delirium in outpatient geriatric patients and also hospitalized patients.

Conditions

Delirium in Old Age; Delirium Superimposed on Dementia; Delirium With Dementia

Keywords

Delirium; Dementia; Mortality; Etiology; Outpatient

Outcome Measures

Primary Outcomes (1)

• frequency of Mortality

  1st year mortality according to the electronic national data base

  1 year fellow-up

Study Arms (4)

Delirium with dementia

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Diagnostic Test: Confussion assessment method (CAM); Diagnostic Test: Dementia diagnosis

Dementia without Delirium

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Diagnostic Test: Dementia diagnosis

Delirium without Dementia

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Diagnostic Test: Confussion assessment method (CAM)

No dementia, No delirium

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Interventions

Confussion assessment method (CAM) DIAGNOSTIC_TEST

Participants enrolled in the Delirium group according to the CAM.

Delirium with dementia; Delirium without Dementia

Dementia diagnosis DIAGNOSTIC_TEST

Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria

Delirium with dementia; Dementia without Delirium

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Community-dwelling older adults (65 years and older)

You may qualify if:

• We included all 65 years older patients who evaluated according to a comprehensive geriatric assessment that is consistently performed during admission to the outpatients' clinic of the hospital.

Sponsors & Collaborators

• Gulhane Training and Research Hospital: lead

Study Sites (1)

Gulhane training and research hospital

Ankara, 06670, Turkey (Türkiye)

RECRUITING

Related Publications (1)

• Katipoglu B, Demircan SK, Naharci MI. Association of drug burden index with delirium in community-dwelling older adults with dementia: a longitudinal observational study. Int J Clin Pharm. 2023 Oct;45(5):1267-1276. doi: 10.1007/s11096-023-01551-7. Epub 2023 Mar 18.

  PMID: 36933080 DERIVED

MeSH Terms

Conditions

Delirium; Dementia

Condition Hierarchy (Ancestors)

Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; Brain Diseases; Central Nervous System Diseases

Study Officials

• Mehmet Naharcı

  Saglik Bilimleri Universitesi

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bilal Katipoglu, MD

CONTACT

+905543330380; drbilal07@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 4, 2021
• First Posted: July 22, 2021
• Study Start: August 5, 2021
• Primary Completion: October 5, 2022
• Study Completion: November 11, 2025
• Last Updated: October 25, 2022

Record last verified: 2022-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)