The Effects of Sex and Age Differences on Gastric Cancer : a Retrospective Study

NCT04973631 | Completed

• 1 other identifier: B-2006-618-004
• Study Type: observational
• Target: 14,900
• Locations: 0 countries
• Sites: N/A

Brief Summary

Gastric cancer (GC) is more prevalent in males than in females. One of these differences could be the effect of sex hormones such as estrogens. However, few reports have been reported regarding sex and age differences of incidence and survival of GC. The aim of this study was to evaluate the effect of sex and age on the incidence and survival of GC. And we would like to further analyze single GC and synchronous multiple GC, EBV, etc.

Conditions

Sex; Age; Gastric Cancer

Outcome Measures

Primary Outcomes (2)

• Survival rate

  Survival rate of gastric cancer on sex and age

  up to 120 months

• histologic type

  histologic type of gastric cancer on sex and age

  about 18 years

Interventions

Sex, Age GENETIC

Evaluate the effect of sex and age on the incidence and survival of GC.

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients diagnosed with Gastric cancer at the Seoul National University Bundang Hospital were analyzed retrospectively from May 2003 to February 2020. The data were collected using clinical data warehouses (CDW), and electronic medical records (EMR) were reviewed as needed.

You may qualify if:

• Clinical diagnosis of Gastric cancer

You may not qualify if:

• Gastric MALTOMA
• Gastric Lymphoma
• Gastrointestinal stromal tumors (GISTs)

Sponsors & Collaborators

• Seoul National University Bundang Hospital: lead

Related Publications (3)

• Song DH, Kim N, Jo HH, Kim S, Choi Y, Oh HJ, Lee HS, Yoon H, Shin CM, Park YS, Lee DH, Kang SH, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH, Ahn S, Surh YJ. Analysis of Characteristics and Risk Factors of Patients with Single Gastric Cancer and Synchronous Multiple Gastric Cancer among 14,603 Patients. Gut Liver. 2024 Mar 15;18(2):231-244. doi: 10.5009/gnl220491. Epub 2023 Mar 29.

  PMID: 36987384 DERIVED

• Jo HH, Kim N, Oh HJ, Song DH, Choi Y, Park J, Lee J, Yoon H, Shin CM, Park YS, Lee DH, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH, Ahn S. The Clinicopathological Features of Mixed Carcinoma in 7,215 Patients with Gastric Cancer in a Tertiary Hospital in South Korea. Gut Liver. 2023 Sep 15;17(5):731-740. doi: 10.5009/gnl220254. Epub 2022 Dec 13.

  PMID: 36510778 DERIVED

• Jo HH, Kim N, Jang J, Choi Y, Park J, Park YM, Ahn S, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH. Impact of Body Mass Index on Survival Depending on Sex in 14,688 Patients with Gastric Cancer in a Tertiary Hospital in South Korea. Gut Liver. 2023 Mar 15;17(2):243-258. doi: 10.5009/gnl220104. Epub 2022 Nov 1.

  PMID: 36317512 DERIVED

MeSH Terms

Conditions

Coitus; Stomach Neoplasms

Interventions

Sex; Aging

Condition Hierarchy (Ancestors)

Sexual Behavior; Behavior; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases

Intervention Hierarchy (Ancestors)

Reproductive Physiological Phenomena; Reproductive and Urinary Physiological Phenomena; Growth and Development; Physiological Phenomena

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 13, 2021
• First Posted: July 22, 2021
• Study Start: May 1, 2003
• Primary Completion: September 1, 2021
• Study Completion: January 1, 2022
• Last Updated: April 13, 2023

Record last verified: 2023-04