NCT04969640

Brief Summary

To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jul 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 25, 2021

Completed
6 days until next milestone

Study Start

First participant enrolled

July 1, 2021

Completed
20 days until next milestone

First Posted

Study publicly available on registry

July 21, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

March 29, 2023

Status Verified

March 1, 2023

Enrollment Period

6 months

First QC Date

June 25, 2021

Last Update Submit

March 28, 2023

Conditions

Infective Keratitis

Outcome Measures

Primary Outcomes (2)

  • criteria of lesion on optical coherence tomography

    Localiztion, depth of infiltration area in microns

    1 month

  • width of lesion on optical coherence tomography

    width of infiltration in microns

    1 month

Study Arms (1)

infective keratitis

50 cases with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Other: Optical coherence tomography

Interventions

Optical coherence tomographyOTHER

Anterior segment optical coherence tomography examination of corneas with infective keratitis

infective keratitis

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any case with infective keratitis

You may qualify if:

  • Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

You may not qualify if:

  • Cases with healed infectious keratitis.
  • Cases presented from the start with severe corneal affection and melting.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Medicine

Minya, Egypt

Location

MeSH Terms

Interventions

Tomography, Optical Coherence

Intervention Hierarchy (Ancestors)

Tomography, OpticalOptical ImagingDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisTomographyInvestigative Techniques

Study Officials

  • Ahmed Abdelghany, ASS PROF

    Minia University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

June 25, 2021

First Posted

July 21, 2021

Study Start

July 1, 2021

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

March 29, 2023

Record last verified: 2023-03

Locations

EG(1)