Carpal Tunnel Syndrome, Right/Left Judgement

NCT04967144 | Completed

• 1 other identifier: 2021/40
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The discrimination of the right/left side of the body is related to the integrity of the motor and somatosensory areas at the cortical and subcortical levels. Although some studies have shown that there may be an effect on the right/left representation at the cortical and subcortical levels in cases that cause severe neuropathy and neuropathic pain, this effect has not been proven in milder neuropathies. In this study, the effect on right/left side discrimination will be investigated even in cases with carpal tunnel syndrome. Additionally, the investigators aimed to assess the relationship between right/left discrimination and symptom severity.

Conditions

Carpal Tunnel Syndrome

Keywords

Carpal tunnel syndrome, body schema

Outcome Measures

Primary Outcomes (1)

• Left/right judgement Task

  The Recognize tablet application will be used within the scope of the 'Graded Motor Imagery' set, in the series of publications created by www.noigroup.com right/left side judgement. The application will be performed on a single tablet screen. Within the scope of the application, right and left-hand pictures will be shown to the participants in varying positions and angles at 5-second intervals. The test consists of 50 pictures. At the end of the test, the accuracy rate and the average reaction time will be calculated separately for the right and left sides.

  3 months

Secondary Outcomes (5)

• Handgrip strength

  3 months

• Two-point discrimination test

  3 months

• Visual Analogue Scale

  3 months

• PainDETECT questionnaire

  3 months

• Boston Carpal Tunnel Questionnaire

  3 months

Study Arms (2)

Carpal Tunnel syndrome

.Patients with carpal tunnel syndrome

Diagnostic Test: Nerve conduction study; Diagnostic Test: Montreal Cognitive Assessment Test

Control subjects

Healthy subjects

Diagnostic Test: Nerve conduction study; Diagnostic Test: Montreal Cognitive Assessment Test

Interventions

Nerve conduction study DIAGNOSTIC_TEST

Participants with carpal tunnel syndrome will consist of individuals whose diagnosis has been confirmed by an electrophysiological study. Participants in the control group will consist of those who have been confirmed not to have carpal tunnel syndrome by nerve conduction study.

Carpal Tunnel syndrome; Control subjects

Montreal Cognitive Assessment Test DIAGNOSTIC_TEST

Montreal Cognitive Assessment Test evaluates eight separate cognitive functions. Thirty is the highest score. The scores equal to or above 26 are considered normal cognitive function.

Carpal Tunnel syndrome; Control subjects

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Carpal Tunnel Syndrome

You may qualify if:

• Participants with a duration of symptoms associated with unilateral CTS of at least 3 months
• Participants with clinically and nerve conduction study confirmed carpal tunnel syndrome
• All participants will be right-hand dominance and diagnosed with carpal tunnel syndrome on the same side
• Participants with MOCA score minimum 26.

You may not qualify if:

• Severe visual impairment that may prevent performing the test
• Polyneuropathy
• Cervical spine surgery history
• Presence of abnormal cervical spine, shoulder, and elbow joint examination findings
• Patients with any history of surgery for the upper extremity
• Congenital/Developmental upper extremity malformations
• Central nervous system disease
• Antihistaminic, gabapentinoids, antiepileptics, methylphenidate, modafinil, neuroleptics use

Sponsors & Collaborators

• Bozyaka Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences Izmir Bozyaka Training and Research Hospital

Izmir, Karabaglar, Turkey (Türkiye)

Location

Related Publications (5)

• Breckenridge JD, Ginn KA, Wallwork SB, McAuley JH. Do People With Chronic Musculoskeletal Pain Have Impaired Motor Imagery? A Meta-analytical Systematic Review of the Left/Right Judgment Task. J Pain. 2019 Feb;20(2):119-132. doi: 10.1016/j.jpain.2018.07.004. Epub 2018 Aug 9.

  PMID: 30098404 BACKGROUND

• Schmid AB, Coppieters MW. Left/right judgment of body parts is selectively impaired in patients with unilateral carpal tunnel syndrome. Clin J Pain. 2012 Sep;28(7):615-22. doi: 10.1097/AJP.0b013e31823e16b9.

  PMID: 22688599 RESULT

• Moseley GL. Why do people with complex regional pain syndrome take longer to recognize their affected hand? Neurology. 2004 Jun 22;62(12):2182-6. doi: 10.1212/01.wnl.0000130156.05828.43.

  PMID: 15210879 RESULT

• Williams LJ, Braithwaite FA, Leake HB, McDonnell MN, Peto DK, Lorimer Moseley G, Hillier SL. Reliability and validity of a mobile tablet for assessing left/right judgements. Musculoskelet Sci Pract. 2019 Apr;40:45-52. doi: 10.1016/j.msksp.2019.01.010. Epub 2019 Jan 24.

  PMID: 30703633 RESULT

• Akcay S, Koskderelioglu A, Ince B, Elif Saka F, Eskut N, Goksel Karatepe A. Is the left/right judgment task performance altered in unilateral carpal tunnel syndrome: And associated with symptom severity? Musculoskelet Sci Pract. 2022 Dec;62:102641. doi: 10.1016/j.msksp.2022.102641. Epub 2022 Aug 4.

  PMID: 35961062 DERIVED

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Nerve Conduction Studies

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Neurological; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis

Study Officials

• Seniz Akcay, Assoc Prof

  University of Health Sciences Izmir Bozyaka Training and Research Hospital

  STUDY DIRECTOR

• Altinay Goksel Karatepe, Prof

  University of Health Sciences Izmir Bozyaka Training and Research Hospital

  STUDY CHAIR

• Fikriye Elif Saka, MD

  University of Health Sciences Izmir Bozyaka Training and Research Hospital

  STUDY CHAIR

• Asli Koskderelioglu, Assoc Prof

  University of Health Sciences Izmir Bozyaka Training and Research Hospital

  STUDY CHAIR

• Neslihan Eskut, Specialist

  University of Health Sciences Izmir Bozyaka Training and Research Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Study Director

Study Record Dates

• First Submitted: July 8, 2021
• First Posted: July 19, 2021
• Study Start: July 19, 2021
• Primary Completion: December 30, 2021
• Study Completion: December 30, 2021
• Last Updated: February 22, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)