The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)

NCT04966689 | Completed

• 1 other identifier: 1
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Speech and voice disorders are observed in almost 90% of patients with PD during their course of illness. Reduced voice pitch inflections or monotone speech, reduced vocal loudness, prosody disorders, the imprecise articulation of the consonants, hoarseness, and breathy voice is also observed in patients with PD; these symptoms often lead to reduced speech intelligibility. The aim of this study will to investigate the possible changes in the voice and speech features in people with PD after a combined speech and music therapy using Telerehabilitation.

Conditions

Speech Disorders; Voice Disorders; Parkinson Disease

Outcome Measures

Primary Outcomes (1)

• loudness

  Change in loudness over the period of the study which will be based on analysis of acoustic recordings. Loudness of voice will be measured in produce the vowel /a /, reading and spontaneous speech. Data will be analyzed using Praat, freeware program for the analysis and reconstruction of acoustic speech signals.

  Change from Baseline in loudness at 4 weeks and 3 month follow up

Secondary Outcomes (11)

• Voice Handicap Index (VHI)

  Change from Baseline in VHI at 4 weeks and 3 month follow up

• maximum phonation time (MPT)

  Change from Baseline in MPT at 4 weeks and 3 month follow up

• Speech Intelligibility

  Change from Baseline in Speech Intelligibility at 4 weeks and 3 month follow up

• Swallowing Disturbance Questionnaire (SDQ)

  Change from Baseline in SDQ at 4 weeks and 3 month follow up

• Dysphagia handicap index (DHI)

  Change from Baseline in DHI at 4 weeks and 3 month follow up

Study Arms (3)

combined speech and music therapy

EXPERIMENTAL

the telerehabilitation intervention that include both speech therapy and music therapy at the same time

Behavioral: combined speech and music therapy

speech therapy

ACTIVE COMPARATOR

A behavioural speech therapy program including breathing exercises, loudness, pitch, and intelligibility which are adapted from Lee Silverman Voice Treatment (LSVT) and voice exercises Which is delivered through telerehabilitation

Behavioral: speech therapy

music therapy

ACTIVE COMPARATOR

music exercises Will be designed based on the music therapy protocols of previous studies Which is delivered through telerehabilitation

Behavioral: music therapy

Interventions

combined speech and music therapy BEHAVIORAL

he telerehabilitation intervention that include both speech therapy and music therapy at the same time

combined speech and music therapy

speech therapy BEHAVIORAL

A behavioural speech therapy program including breathing exercises, loudness, pitch, and intelligibility which are adapted from Lee Silverman Voice Treatment (LSVT) and voice exercises Which is delivered through telerehabilitation

speech therapy

music therapy BEHAVIORAL

music exercises Will be designed based on the music therapy protocols of previous studies Which is delivered through telerehabilitation

music therapy

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with idiopathic Parkinson's disease (IPD)
• Patients who are in stages 1-3 according to Hoehn \& Yahr test
• Native language is persian
• The patient or family complains about the person's speech condition
• Adequate vision and hearing
• No history of stroke, head injury, brain surgery, laryngeal diseases such as vocal cord nodules
• No other neurological disorders other than IPD
• Do not use treatment other than medication (such as deep brain stimulation surgery (DBS)
• informed consent

You may not qualify if:

• If a patient develops a stroke or other neurological complication during treatment, they are excluded from the treatment
• Lack of cooperation

Sponsors & Collaborators

• Iran University of Medical Sciences: lead

Study Sites (1)

Iran University of Medical Sciences

Tehran, Iran

Location

Related Publications (1)

• Mohseni Z, Mohamadi R, Habibi SAH, Saffarian A, Abolghasemi J. Voice improvement following conventional speech therapy combined with singing intervention in people with Parkinson's disease: A three-arm randomised controlled trial. Int J Lang Commun Disord. 2023 Sep-Oct;58(5):1752-1767. doi: 10.1111/1460-6984.12900. Epub 2023 Jun 7.

  PMID: 37282797 DERIVED

MeSH Terms

Conditions

Speech Disorders; Voice Disorders; Parkinson Disease

Interventions

Music Therapy; Speech Therapy

Condition Hierarchy (Ancestors)

Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Laryngeal Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Intervention Hierarchy (Ancestors)

Sensory Art Therapies; Complementary Therapies; Therapeutics; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Psychotherapy; Behavioral Disciplines and Activities; Rehabilitation of Speech and Language Disorders

Study Officials

• Reyhaneh Mohammadi

  Iran university of medical science

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 30, 2021
• First Posted: July 19, 2021
• Study Start: July 17, 2021
• Primary Completion: January 7, 2022
• Study Completion: January 30, 2022
• Last Updated: April 4, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)