NCT04956614

Brief Summary

This study is a prospective randomized controlled clinical study. After the novel Achilles tendon rupture repaired , patients were randomly divided into 4 groups according to immobilisation duration of 0, 2, 4, and 6 weeks, respectively. All patients underwent the same suture technique with a similar rehabilitation protocol and were examined clinically at 2, 4, 6, 8, 10, 12, 14, 16, 24, and 48 weeks to study the difference in efficacy among the groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
266

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2018

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2020

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2021

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

July 2, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 9, 2021

Completed
Last Updated

July 9, 2021

Status Verified

July 1, 2021

Enrollment Period

2 years

First QC Date

July 2, 2021

Last Update Submit

July 2, 2021

Conditions

Keywords

Duration of immobilisation

Outcome Measures

Primary Outcomes (1)

  • The time of return to light sports activity

    When the patients are able to do jogging or rapid walk after the surgery, the time will be recorded

    From operation to 1-year follow-up after the surgery

Secondary Outcomes (2)

  • Range of motion (ROM) recovery time

    From operation to 1-year follow-up after the surgery

  • Recovery time of the single-legged heel rise height (SHRH)

    From operation to 1-year follow-up after the surgery

Other Outcomes (3)

  • visual analogue scale (VAS)

    2, 4, 6, 8, 10, 12, 14, 16, 24, and 48 weeks after the surgery

  • American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score

    2, 4, 6, 8, 10, 12, 14, 16, 24, and 48 weeks after the surgery

  • the Achilles tendon Total Rupture Score (ATRS)

    2, 4, 6, 8, 10, 12, 14, 16, 24, and 48 weeks after the surgery

Study Arms (2)

suture of Achilles tendon without immobilisation

EXPERIMENTAL
Device: immobilisation duration

suture of Achilles tendon with immobilisation

EXPERIMENTAL
Device: immobilisation duration

Interventions

immobilisation duration of 2,4,6 week after suture of Achilles tendon

suture of Achilles tendon with immobilisationsuture of Achilles tendon without immobilisation

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patients aged 18 to 60 years with an acute closed single-legged complete ATR who underwent open surgery with our suture technique.

You may not qualify if:

  • patients with prior Achilles tendon rupture or other situations that affected their lower limb functions or tendon healing (e.g., autoimmune disease, diabetes mellitus, systemic corticosteroid treatment).
  • an inability to complete our suture technique (e.g., the distance from the rupture site to the Achilles tendon insertion was less than 3.5 cm) .
  • those without rehabilitation or follow-up outcomes.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking University Third Hospital

Beijing, Beijing Municipality, 100191, China

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 2, 2021

First Posted

July 9, 2021

Study Start

July 1, 2018

Primary Completion

July 1, 2020

Study Completion

July 1, 2021

Last Updated

July 9, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

Locations