A Comparative Study of High and Low Tidal Volume in Preventing Hypoxemia in Patients With Mechanical Ventilation After Cervical Spinal Cord Injury

NCT04949971 | Unknown

• 1 other identifier: LM2020353
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study in order to best tidal volume mechanical ventilation in patients with cervical spinal cord injury (sci) as the research point, through higher low volume Settings to find the difference of two groups of patients to prevent the incidence of hypoxemia, to find suitable Settings, tidal volume in patients with lower mechanical ventilation in patients with cervical spinal cord injury (sci) the incidence of pulmonary complications, live less intensive care unit (ICU).

Conditions

Cervical Spinal Cord Injury

Outcome Measures

Primary Outcomes (1)

• The incidence of hypoxemia

  The oxygenation index is less than 300

  during machinical ventilation

Study Arms (2)

High volume group

The tidal volume of the exposed group was 10ml/kg ideal body weight.

Low volume group

The tidal volume of the non-exposed group was 6ml/kg ideal body weight

Behavioral: High volume group

Interventions

High volume group BEHAVIORAL

Thea High tidal volume of the exposed group was 10ml/kg ideal body weight

Also known as: Low volume group

Low volume group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

① Above the age of 18; ② Patients with cervical spinal cord injury requiring mechanical ventilation admitted to hospital.

You may qualify if:

• All critically ill adult patients with cervical spinal cord injury who require mechanical ventilation and informed consent to be admitted to the Department of Critical Care Medicine of Peking University Third Hospital were selected by the subjects or their close relatives to enter the clinical study.

You may not qualify if:

• previous chronic obstructive pulmonary disease, diagnosis of acute respiratory distress syndrome at admission, presence of pneumothorax at admission, subjects or close relatives who refused to participate in the study, and non-signed informed consent."

Sponsors & Collaborators

• Peking University Third Hospital: lead

Study Sites (1)

Xuelei

Beijing, Beijing Municipality, 100191, China

RECRUITING

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2021
• First Posted: July 2, 2021
• Study Start: April 3, 2021
• Primary Completion: May 31, 2022
• Study Completion: December 31, 2022
• Last Updated: July 2, 2021

Record last verified: 2020-08

Locations

CN (1)