NCT04949581

Brief Summary

The aim of this study is to investigate the effect of bioelectric therapy on sternal instability in patients with median sternotomy after heart valve surgery.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2021

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 25, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 2, 2021

Completed
13 days until next milestone

Study Start

First participant enrolled

July 15, 2021

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2021

Completed
Last Updated

July 2, 2021

Status Verified

June 1, 2021

Enrollment Period

3 months

First QC Date

June 25, 2021

Last Update Submit

June 25, 2021

Conditions

Keywords

bioelectric therapymedian sternotomyheart valve surgery

Outcome Measures

Primary Outcomes (1)

  • sternal instability

    sternal instability scale will be used for assessment. this scale has four points. zero mean more stability and three mean completly separated

    up to four weeks

Secondary Outcomes (1)

  • sternal separation

    up to four weeks

Study Arms (2)

bioelectric therapy

EXPERIMENTAL

patients will receive micro-current electrical stimulation three times/week for four weeks

Other: bioelectric therapyOther: cardiac rehabilitation program

cardiac rehabilitation programe

ACTIVE COMPARATOR

patients will receive a cardiac rehabilitation program three times/week for four weeks

Other: cardiac rehabilitation program

Interventions

the patient will receive microcurrent therapy from a supine lying position. the negative electrode on the incision area and the positive electrode proximal. the intensity will be less than 20 microamperes and frequency at 20 HZ.

bioelectric therapy

the patient will receive cardiac rehabilitation program

bioelectric therapycardiac rehabilitation programe

Eligibility Criteria

Age40 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • there age between 40 and 50 years,
  • hemodynamic stability
  • BMI from 25 to 29.9 kg/m2,
  • they will have acute sternal instability.

You may not qualify if:

  • previous thoracic surgery
  • elective and urgent coronary artery bypass surgery
  • respiratory insufficiency after surgery manifesting hypoxemia with partial pressure of oxygen in arterial blood \<60 mmHg
  • renal insufficiency with serum creatinine ≥1.8 mg/dl after surgery
  • low cardiac output syndrome with ST segment elevation in multiple electrocardiogram leads, cardiac arrhythmias, or hypotension, according to the American College of Cardiology Foundation and American Heart Association

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

al shaymaa sh abd el azeim, lecturer

CONTACT

al shaymaa sh abd el azeim, lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
random generator
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: bioelectric therapy and routine cardiac rehabilitation program
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
al shaymaa shaaban abd el azeim

Study Record Dates

First Submitted

June 25, 2021

First Posted

July 2, 2021

Study Start

July 15, 2021

Primary Completion

September 30, 2021

Study Completion

September 30, 2021

Last Updated

July 2, 2021

Record last verified: 2021-06