NCT04947332

Brief Summary

This study is being conducted to see effectiveness of auto-inoculation of a wart in multiple viral warts. Patients with recurrent, multiple warts of all types, are being recruited for the study. A wart is excised, minced and then inoculated in a subcutaneous pocket made on the volar aspect of forearm. Patients are to be reviewed after every 4 weeks to note any reduction in number warts.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 8, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 19, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

July 1, 2021

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2022

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 10, 2022

Completed
Last Updated

January 13, 2022

Status Verified

January 1, 2022

Enrollment Period

12 months

First QC Date

June 19, 2021

Last Update Submit

January 12, 2022

Conditions

Viral WartDelayed Hypersensitivity

Keywords

AutoinoculationViral WartsHypersensitivityImmunology

Outcome Measures

Primary Outcomes (3)

  • Complete Clearance of Warts

    All the warts on any part of the body are cleared

    12 weeks

  • Incomlete Clearance of Warts

    No or size of warts are reduced

    12 weeks

  • Non Responders

    If no change or increased no of warts

    12 weeks

Study Arms (1)

Auto-inoculation recipients

OTHER

Auto-inoculation of wart to be performed

Procedure: Auto-inoculation

Interventions

Auto-inoculationPROCEDURE

A wart will be excised from the body, minced and will be inoculated in a subcutaneous pocket on forearm.

Auto-inoculation recipients

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals having 5 or warts
  • Individuals having any types of warts

You may not qualify if:

  • Individuals using any other treatment for warts

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pak Emirates Military Hospital

Rawalpindi, Punjab Province, Pakistan

RECRUITING

MeSH Terms

Conditions

WartsHypersensitivity, DelayedHypersensitivity

Condition Hierarchy (Ancestors)

Papillomavirus InfectionsDNA Virus InfectionsVirus DiseasesInfectionsSkin Diseases, ViralTumor Virus InfectionsSkin Diseases, InfectiousSkin DiseasesSkin and Connective Tissue DiseasesImmune System Diseases

Study Officials

  • Nadia Iftikhar, MBBS, FCPS

    Head of Department

    STUDY DIRECTOR

Central Study Contacts

Waseem Shahid, MBBS

CONTACT

+923347202392waseem902@yahoo.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: A single arm study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident Dermatology

Study Record Dates

First Submitted

June 19, 2021

First Posted

July 1, 2021

Study Start

February 8, 2021

Primary Completion

January 31, 2022

Study Completion

February 10, 2022

Last Updated

January 13, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)