NCT04937192

Brief Summary

The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2012

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
9.4 years until next milestone

First Submitted

Initial submission to the registry

June 10, 2021

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 23, 2021

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

October 25, 2022

Status Verified

October 1, 2022

Enrollment Period

11 years

First QC Date

June 10, 2021

Last Update Submit

October 23, 2022

Conditions

Keywords

SNPKidney stoneRecurrence

Outcome Measures

Primary Outcomes (1)

  • Stone-free survival

    Time to first stone recurrence from stone-free

    From date of stone-free until the date of first stone recurrence (up to 7 years)

Study Arms (1)

Kidney stone former

Other: No intervention

Interventions

No intervention

Kidney stone former

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Kidney stone former who the stone was removed completely

You may qualify if:

  • Age 18 or older
  • Kidney stone former who the stone was removed completely.
  • Ability to give informed consent

You may not qualify if:

  • Patient refuses or is unable to give consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, 510120, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Blood was obtained for DNA

MeSH Terms

Conditions

Kidney CalculiRecurrence

Condition Hierarchy (Ancestors)

NephrolithiasisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrolithiasisUrinary CalculiMale Urogenital DiseasesCalculiPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Study Officials

  • Guohua Zeng, M.D.

    The First Affiliated Hospital of Guangzhou Medical University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Guohua Zeng, M.D.

CONTACT

Wei Zhu, M.D.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Vice president

Study Record Dates

First Submitted

June 10, 2021

First Posted

June 23, 2021

Study Start

January 1, 2012

Primary Completion

December 31, 2022

Study Completion

December 31, 2023

Last Updated

October 25, 2022

Record last verified: 2022-10

Locations