NCT04933487

Brief Summary

This is a single-center, prospective PMCF study whereby patients undergoing routine cataract surgery will have monolateral implantation of hydrophilic monofocal toric intraocular lens Ankoris.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 26, 2014

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
3.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2019

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

June 18, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 21, 2021

Completed
Last Updated

June 21, 2021

Status Verified

June 1, 2021

Enrollment Period

1.4 years

First QC Date

June 18, 2021

Last Update Submit

June 18, 2021

Conditions

Keywords

Intraocular LensMonofocalToric Lens

Outcome Measures

Primary Outcomes (1)

  • Rotational stability - Photograph of IOL with dilated pupil to asses IOL rotation

    Rotational stability of the ANKORIS is evaluated on the basis of slit-lamp photographies to capture the iris and the marks onto the lens. Descriptive statistics will be used to determine the IOL stability.

    3 months postoperative

Secondary Outcomes (1)

  • Residual astigmatism after Ankoris implantation with respect to the targeted astigmatism correction.

    Follow-ups will be performed 1 day, 1 month, and 3 months after cataract surgery

Study Arms (1)

Ankoris IOL Implantation experimental

EXPERIMENTAL

Monolateral implantation of toric intraocular lenses Ankoris

Device: IOL implantation experimental

Interventions

Monolateral implantation of toric intraocular lenses Ankoris. (Manufactured by PhysIOL sa/nv, Liège, Belgium).

Ankoris IOL Implantation experimental

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Cataracteous Eyes with no comorbidity
  • Regular corneal astigmatism \>1 dioptre and \<3D determined by an automatic keratometer (regularity determined by the topography of the keratometry).
  • Availability, willingness and sufficient cognitive awareness to comply with examination procedures
  • Signed informed consent •\>50 years old

You may not qualify if:

  • Acute or chronic disease or illness that would increase risk or confound study results (e.g. diabetes mellitus (with retinopathy), immunocompromised, glaucoma etc…)
  • Any ocular comorbidity
  • History of ocular trauma or prior ocular surgery including refractive procedures
  • Capsule or zonular abnormalities that may affect postoperative centration or tilt of the lens (e.g. pseudoexfoliation syndrome, Marfan's syndrome)
  • Pupil abnormalitis (non-reactive, tonic pupils, abnormally shaped pupils or pupils that do not dilate under mesopic/scotopic conditions)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ruhr-Universitat Bochum, Bochum, Germany

Bochum, Germany

Location

MeSH Terms

Conditions

CataractAstigmatism

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesRefractive Errors

Study Officials

  • Burkhard Dick, MD

    Ruhr-Universitat Bochum, Bochum, Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2021

First Posted

June 21, 2021

Study Start

August 26, 2014

Primary Completion

January 1, 2016

Study Completion

March 1, 2019

Last Updated

June 21, 2021

Record last verified: 2021-06

Data Sharing

IPD Sharing
Will not share

Locations