Antibiotic Regimens Tailored by Clinical Pharmacist Suppored by Intensivist Enhanced Rational Use of Antibiotics

NCT04931914 | Completed

• 1 other identifier: 203
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

adding pharmaceutical services to patient care and changing the professional activity of pharmacists from drug-focused to patient-oriented care,in the current study, clinical pharmacists will be assigned to monitor pharmacotherapy regimens, participate in patient care, and cooperate in educating the staff and evaluating care.

Conditions

Critical Illness

Outcome Measures

Primary Outcomes (3)

• Antibiotics consumption

  consumption will be counted as number of defined daily doses (DDD), expressed as DDD per 100 patient-days

  1 year

• Average length of stay

  the average number of days that patients spent in SICU.

  1 year

• Mortality rate

  The number of deaths of patients admitted to SICU, divided by the number of admissions.

  1 year

Study Arms (1)

Group c

Patients admitted from June 9, 2020 to june 31, 2021.

Other: Clinical pharmacy sharing in the patient care regimen

Interventions

Clinical pharmacy sharing in the patient care regimen OTHER

antibiotic regimens will be directed by a trained clinical pharmacist recommendation and supported by intensivist.

Group c

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All the information including the age, gender, comorbidity (presented as Charlson comorbidity index score ), surgical procedure done, patients' temperature, white blood cells count, type of infection (e.g., pneumonia, wound infection, Urinary tract infection,…..), prescribed antibiotics regimen either they will use empirical or based on cultures, results of culture sensitivity tests, length of stay, and mortality of patients

You may qualify if:

• all admitted patients to the ICU between age 18-80 years old

You may not qualify if:

• Patient admitted for less than 24 hours (including deaths and transfers) will be excluded from the study.
• Pediatric patients weighted less than kilograms.

Sponsors & Collaborators

• University of Alexandria: lead

Study Sites (1)

Alexandria university

Alexandria, 23541, Egypt

Location

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer in the anaesthesia department Alexandria university

Study Record Dates

• First Submitted: May 29, 2021
• First Posted: June 18, 2021
• Study Start: January 4, 2020
• Primary Completion: December 5, 2020
• Study Completion: December 25, 2020
• Last Updated: November 9, 2022

Record last verified: 2022-11

Locations

EG (1)