NCT04929184

Brief Summary

This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
143

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2022

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 10, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 18, 2021

Completed
10 months until next milestone

Study Start

First participant enrolled

April 4, 2022

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 16, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 16, 2025

Completed
Last Updated

July 3, 2025

Status Verified

July 1, 2025

Enrollment Period

3.2 years

First QC Date

June 10, 2021

Last Update Submit

July 1, 2025

Conditions

Keywords

Healthy childrenHealthy Adults

Outcome Measures

Primary Outcomes (2)

  • Phase locking value (PLV) - Session 1 speech tasks

    The degree of synchronization will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals.

    Session 1 (up to 4 hours)

  • Phase locking value (PLV) - Session 2 speech tasks

    The degree of synchronization will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals. Session 2 is for adults only.

    Session 2 (up to 4 hours)

Secondary Outcomes (1)

  • Phase locking value (PLV) - Non-speech tasks

    Session 1 (up to 4 hours)

Study Arms (4)

Adults who stutter (AWS)

EXPERIMENTAL

Participants will have 2 visits.

Behavioral: Speech and non-speech tasks

Healthy Adults

OTHER

Participants will have 2 visits.

Behavioral: Speech and non-speech tasks

Children who Stutter

EXPERIMENTAL

Participants will have 1 visit.

Behavioral: Speech and non-speech tasks

Healthy Children

OTHER

Participants will have 1 visit.

Behavioral: Speech and non-speech tasks

Interventions

Participants will complete speech tasks such as listening to and/or producing speech and non-speech sounds.

Adults who stutter (AWS)Children who StutterHealthy AdultsHealthy Children

Eligibility Criteria

Age6 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • years old
  • English as primary language
  • Normal speech, language, hearing, cognition

You may not qualify if:

  • Personal or family history of stuttering
  • Major medical or psychiatric illness
  • Aged 18-65 years
  • English as primary language
  • Normal speech, language, hearing, cognition (other than stuttering)
  • Currently stutters
  • Speech therapy within the past year
  • Major medical or psychiatric illness
  • Aged 6 to 17 years
  • English as primary language
  • Normal speech, language, hearing, cognition
  • Personal or family history of stuttering
  • Major medical or psychiatric illness
  • Language/motor delay
  • Aged 6 to 17 years
  • +5 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

Michigan State University

East Lansing, Michigan, 48824, United States

Location

MeSH Terms

Conditions

Stuttering

Condition Hierarchy (Ancestors)

Speech DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Emily Garnett, PhD

    University of Michigan

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Investigator

Study Record Dates

First Submitted

June 10, 2021

First Posted

June 18, 2021

Study Start

April 4, 2022

Primary Completion

June 16, 2025

Study Completion

June 16, 2025

Last Updated

July 3, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations