Risk Factors for Long-term Opioid Use

NCT04928131 | Completed

• 1 other identifier: 43803
• Study Type: observational
• Target: 1,500,392
• Locations: 0 countries
• Sites: N/A

Brief Summary

Surgeons often see patients with pain to exclude organic pathology and consider surgical treatment. We examined factors associated with long-term opioid therapy among patients with foot/ankle, anorectal, and temporomandibular joint pain to aid clinical decision making. Using the IBM MarketScan® Research Database, we conducted a retrospective cohort analysis of patients aged 18-64 with a clinical encounter for foot/ankle, anorectal, or temporomandibular joint pain (January 2007-September 2015). Multivariable logistic regression was used to estimate adjusted odds ratios for factors associated with long-term opioid therapy, including age, sex, geographic region, pain condition, psychiatric diagnoses, and surgical procedures in the previous year.

Conditions

Pain Syndrome

Outcome Measures

Primary Outcomes (1)

• Long-term opioid use

  opioid prescriptions for 3 months.

  >90 days of opioid supply

Secondary Outcomes (1)

• new long-term opioid use

  >90 days of opioid supply

Study Arms (3)

Anorectal

Patients presenting with anorectal pain.

Other: No intervention - retrospective observational cohort study

TMJ

Patients presenting with temporomandibular joint pain.

Other: No intervention - retrospective observational cohort study

Foot/Ankle

Patients presenting with foot and ankle pain.

Other: No intervention - retrospective observational cohort study

Interventions

No intervention - retrospective observational cohort study OTHER

Anorectal; Foot/Ankle; TMJ

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

adult patients enrolled in private health insurance included within the Marketscan database, who generated at least one insurance claim for anorectal, foot/ankle, or TMJ pain.

You may qualify if:

• years old
• at least one encounter for anorectal, foot/ankle, or TMJ pain
• Marketscan continuous enrollment for 1 year prior and 1 year after the index pain encounter

Sponsors & Collaborators

• Stanford University: lead

MeSH Terms

Conditions

Somatoform Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Surgery

Study Record Dates

• First Submitted: June 9, 2021
• First Posted: June 16, 2021
• Study Start: January 1, 2007
• Primary Completion: September 1, 2015
• Study Completion: February 1, 2021
• Last Updated: April 14, 2022

Record last verified: 2022-04