Trials Sponsors Conditions Drugs Pricing

Conditions

Hiv Opioid-use Disorder

Outcome Measures

Primary Outcomes (1)

Average Percentage of Recommended Quality Health Indicator Services Accessed by Participants to Assess Efficacy
The total average percentage of the 17 recommended Quality Health Indicator screenings and services that were accessed by participants to assess efficacy. Recommended QHI screenings are as follows: General medical examination; blood analysis; urine analysis; cardiogram; mammogram; cervical cancer screening; prostate cancer screening; hepatitis B screening; hepatitis C screening; HIV screening; CD4 or viral load; ART treatment; TB screening; TB treatment; received take-home MMT; adequate MMT dose; on MMT for 12 months. Data presented here is for adjusted average values of services accessed at 24 months.
every 6 months up to 24 months

Secondary Outcomes (2)

Average Percentage of Recommended Primary Quality Health Indicator Services Accessed to Assess Efficacy
every 6 months up to 24 months
Average Percentage of Recommended Specialty Quality Health Indicator Services Accessed to Assess Efficacy
every 6 months up to 24 months

Study Arms (3)

Specialty Addiction Clinic

NO INTERVENTION

ECHO-IC/QI-enhanced primary care clinic

EXPERIMENTAL

Other: Integration of HIV and PWID services

ECHO-IC/QI-enhanced primary care clinic with Pay for Performance

ACTIVE COMPARATOR

Other: Integration of HIV and PWID services

Interventions

Integration of HIV and PWID servicesOther

Co-location of clinical services for HIV and PWID patients

ECHO-IC/QI-enhanced primary care clinicECHO-IC/QI-enhanced primary care clinic with Pay for Performance

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

PWID
Interested in MMT

Sponsors & Collaborators

Ukrainian Institute on Public Health Policy
Othercollaborator
National Institute on Drug Abuse (NIDA)
NIHcollaborator

Study Sites (1)

European Institute for Public Health Policy

Kyiv, Ukraine

Related Publications (4)

Machavariani E, Esserman D, Dumchev K, Filippovych M, Pykalo I, Ivasiy R, Madden LM, Bromberg DJ, Haddad M, Morozova O, Oliveros D, Ahmad B, Dvoriak S, Altice FL. Integrating Methadone Services Into Primary Care in Ukraine: Two-Year Outcomes From a Randomized Trial. Ann Intern Med. 2026 Feb;179(2):177-186. doi: 10.7326/ANNALS-25-01764. Epub 2025 Dec 9.
PMID: 41359964DERIVED
Machavariani E, Bromberg DJ, Dumchev K, Esserman D, Earnshaw VA, Pykalo I, Filippovich M, Ivasiy R, Ahmad B, Long J, Haddad MS, Madden LM, Oliveros D, Dvoriak S, Altice FL. Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine. Int J Drug Policy. 2025 Feb;136:104682. doi: 10.1016/j.drugpo.2024.104682. Epub 2024 Dec 19.
PMID: 39705875DERIVED

MeSH Terms

Conditions

Acquired Immunodeficiency SyndromeOpioid-Related Disorders

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital Diseases

Results Point of Contact

Title: Dr. Frederick Altice
Organization: Yale University

Study Officials

Frederick Altice, MD
Yale University
PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee: Yes

Enrollment

1,590 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: PREVENTION
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

June 10, 2021

First Posted

June 15, 2021

Study Start

May 1, 2017

Actual (reported)

Integrating Addiction Treatment and HIV Services Into Primary Care Clinics in Ukraine

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (3)

Specialty Addiction Clinic

ECHO-IC/QI-enhanced primary care clinic

ECHO-IC/QI-enhanced primary care clinic with Pay for Performance

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (4)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Documents

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (3)

Specialty Addiction Clinic

ECHO-IC/QI-enhanced primary care clinic

ECHO-IC/QI-enhanced primary care clinic with Pay for Performance

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (4)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Documents

Locations