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Sponsor study identifier
observational
471
1 country
1
Study Start
October 1, 2018
Actual (reported)Primary Completion
March 30, 2020
Actual (reported)Study Completion
August 15, 2020
Actual (reported)The general aim of this project is to get a better understanding how periodontitis develop in young individuals over time and identify factors that contribute to disease recurrence. The investigators also want to see if Stage and Grade of the periodontal disease has a significant impact on disease progression. In addition, another purpose is to identify factors explaining why certain young patients with periodontitis interrupt the periodontal treatment. The specific aims of the project are:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 15, 2020
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 1, 2018
Actual (reported)March 30, 2020
Actual (reported)August 15, 2020
Actual (reported)October 2, 2020
Actual (reported)June 15, 2021
Actual (reported)Periodontal disease progression in young individuals with periodontitis 10-13 years after baseline
Periodontal progression will be assessed by Periodontitis grade according to The 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions: This is a categorical variable consisting of ordinal data at three levels (A, B, C). A is the lowest progression rate and C is the highest rate. The assessment is performed by comparing the degree of periodontal bone loss between baseline and follow-up.
October 2018 to May 2021
Factors influencing tooth loss over 9 - 11 years in young individuals with periodontitis
2020 to 2022
To identify bio marker and microbiological profiles in young individuals in relation to stage and grade of periodontitis
2020-2023
Patients that got the diagnosis aggressive periodontitis at baseline. Since 2018 we have the classification system with stage and grade why patients get this classification at the clinical examination.
Patients that got the diagnosis chronic periodontitis at baseline. Since 2018 we have the classification system with stage and grade why patients get this classification at the clinical examination.
Identify factors that contribute to disease recurrence due to periodontal classification and periodontal treatment. One group have got the diagnosis aggressive periodontitis at baseline and the other group chronic periodontitis. Since 2018 we have the classification system with stage and grade.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
All patients at age \< 36 years who were examined by a periodontist at two specialist clinics in Stockholm during the years 2003-2009 (baseline) and got the diagnoses aggressive or chronic periodontitis were included in the project. Study group: Patients with diagnosis aggressive periodontitis at baseline Control group: Patients with diagnosis chronic periodontitis at baseline
Folktandvården Eastmaninstitutet
Stockholm, 102 31, Sweden
Bacterial samples from deep periodontal pockets and samples of gingival crevicular fluid from deep periodontal pockets
Leif Jansson, DDSPhDAssPro
Folktandvården Stockholm
471 participants (actual enrollment reported by the registry).
First Submitted
October 2, 2020
First Posted
June 15, 2021
Study Start
October 1, 2018
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
March 30, 2020
Actual (reported)Study Completion
August 15, 2020
Actual (reported)Last Updated
September 29, 2025
Record last verified: 2025-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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