Prevalence of Cardiovascular Risk Factors in Upper Vestibular Neuritis
NEVRITE
1 other identifier
observational
150
1 country
1
Brief Summary
Vestibular neuritis is the second cause of vertigo, it constitutes 5 to 6% of the aetiologies of vertigo in an otoneurological consultation. Infection or reactivation of a neurotropic virus of the herpes group (HSV-1) in the vestibular lymph node is thought to be the cause of the unilateral vestibular deficit. Upper vestibular neuritis is more common than lower, or total involvement. Goebel (2) explains this by an anatomical predisposition of the vestibular nerve canal to inflammation, unlike the singular nerve canal which is shorter and wider giving way to a certain degree of edema without consequence on its contents. However, the innervation territory of the superior vestibular nerve is superimposable on the territory supplied by the anterior vestibular artery. The anterior, lateral semicircular canals and the utricle are affected. Current complementary vestibular and imaging examinations cannot differentiate between inflammatory or vascular involvement in upper vestibular neuritis. The increased presence of cardiovascular risk factors in patients with upper vestibular neuritis would be an argument in favor of ischemic involvement of the anterior vestibular artery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2020
CompletedFirst Submitted
Initial submission to the registry
June 4, 2021
CompletedFirst Posted
Study publicly available on registry
June 15, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 4, 2022
CompletedOctober 7, 2021
June 1, 2021
2 years
June 4, 2021
October 6, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Retrospective study of cardiovascular risk factors in people with upper vestibular neuritis
Files analysed retrospectively from January 01, 2016 to January 31, 2020 will be examined]
Eligibility Criteria
Major having presented an episode of upper vestibular neuritis recorded on the Video Head Impulse Test Ulmer device at the HUS between 01/01/2016 and 01/31/2020,
You may not qualify if:
- Patient who expressed his opposition to participating in the study,
- Total vestibular neuritis,
- impossibility of providing the subject with enlightened information (difficulties in understanding the subject, etc.)
- Subject under safeguard of justice,
- Subject under guardianship or guardianship,
- Lack of video head impulse test data.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Service ORL et de CCF - Hôpitaux Universitaires de Strasbourg
Strasbourg, 67091, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Anne CHARPIOT, MD, PhD
Service ORL et de CCF- Hôpitaux Universitaires de Strasbourg
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 4, 2021
First Posted
June 15, 2021
Study Start
February 1, 2020
Primary Completion
February 1, 2022
Study Completion
February 4, 2022
Last Updated
October 7, 2021
Record last verified: 2021-06