Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's

NCT04919005 | Completed

• 1 other identifier: CAAE: 54290416.9.0000.5497
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This research was carried out with the objective of verifying the possibility of intervention through cognitive training protocols to assist in the stimulation of neurons and to delay the degradation resulting from Alzheimer's disease in its initial phase. The specific objective of this research was to develop and validate a virtual environment of games (called SorrisoTur) that allows the intervention of cognitive training.

Conditions

Alzheimer Disease

Outcome Measures

Primary Outcomes (2)

• Change on Wechsler Intelligence Scale for Adults (WAIS-III)

  The WAIS-III is an intellectual assessment that aims to analise the measures of the following Factorial Scales and Indexes: Verbal IQ (intelligence quotient), Execution IQ, Total IQ, Verbal Understanding Index, Perceptual Organization Indexes, Operational Memory Indexes and Processing speed index.

  Baseline and after 4 weeks

• Change on Mini Mental State Examination (MMSE)

  The MMSE is a data collection instrument widely used in cases of dementia, it evaluates temporal and spatial orientation, short-term memory (immediate or attention) and skills of evocation, calculation, praxis, visuospatial, communication and language.

  Baseline and after 4 weeks

Study Arms (3)

Healthy elderly people

EXPERIMENTAL

Twelve healthy elderly people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Other: Virtual Environment

Elderly people with Alzheimer's in the initial phase

EXPERIMENTAL

Seven elderly people with Alzheimer's in the initial phase. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Other: Virtual Environment

Healthy young people

EXPERIMENTAL

Fifteen healthy young people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Other: Virtual Environment

Interventions

Virtual Environment OTHER

The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Elderly people with Alzheimer's in the initial phase; Healthy elderly people; Healthy young people

Eligibility Criteria

• Age: 19 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• People with physical or psychological conditions allow interacting with digital games;
• Elderly over 60 years with mild Alzheimer;
• Seniors over 60 Healthy;
• Healthy Youth;

You may not qualify if:

• People without physical or psychological conditions allow interacting with digital games;
• Elderly people over 60 years old who have any type of dementia other than Alzheimer, or moderate or severe Alzheimer;

Sponsors & Collaborators

• University of Mogi das Cruzes: lead

Study Sites (1)

Terigi Augusto Scardovelli

Mogi das Cruzes, São Paulo, 08780-911, Brazil

Location

MeSH Terms

Conditions

Alzheimer Disease

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Marcia A Bissaco, PhD

  University of Mogi das Cruzes

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 2, 2021
• First Posted: June 9, 2021
• Study Start: July 1, 2016
• Primary Completion: April 30, 2017
• Study Completion: July 20, 2017
• Last Updated: June 9, 2021

Record last verified: 2021-06

Locations

BR (1)