Laser Correction of Astigmatism Using Vector Analysis

NCT04913883 | Unknown

• 1 other identifier: Adjustment of Astigmatism
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

To determine the effectiveness of correcting astigmatism by laser refractive surgery by a vectorial astigmatism outcome analysis that uses 3 fundamental vectors : target induced astigmatism vector ( TIA) , surgically induced astigmatism vector , and difference vector , as described by Alpins method.

Conditions

Astigmatism

Outcome Measures

Primary Outcomes (1)

• . Post operative Visual Acuity

  To determine the effectiveness of correcting astigmatism by laser refractive surgery by a vectorial astigmatism outcome analysis by : CDVA and UCDVA, pentacam , 3 month, 6 month and 1 year after surgery. * 3 months postoperative : assessment of visual acuity using corrected distance visual acuity (CDVA) , and uncorrected distance visual acuity (UCDVA) and pentacam measures . * 6 months postoperative : assessment of visual acuity using corrected distance visual acuity (CDVA) , and uncorrected distance visual acuity (UCDVA) and pentacam measures . * One year postoperative : assessment of visual acuity using corrected distance visual acuity (CDVA) , and uncorrected distance visual acuity (UCDVA) and pentacam measures .

  one year

Secondary Outcomes (1)

• Postoperative Assessment

  3 months

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Study will include 50 patients in different ages .

You may qualify if:

• At least 18 years of age .
• Stable eyeglass and contact lenses prescription for at least 2 to 3 years .
• Stable vision over at least the past year .
• No history or findings of active corneal disease .
• No significant dry eye .
• Not pregnancy or nursing .
• Refractive cylinder more than -1D (Diopter) .

You may not qualify if:

• Certain conditions make the method inadvisable :
• Residual , recurrent or active ocular disease such as uveitis , sever dry eyes , sever allergic eye disease , glaucoma visually significant cataract , and retinal disease .
• Previous corneal surgery or trauma within the corneal flap zone .
• Patent corneal vascularisation within 1mm of the corneal flap zone .
• Age less than 18 years old .
• Pregnancy or breast feeding .
• Certain medical conditions such as autoimmune diseases (eg. lupus , rheumatoid arthritis), immunodeficiency states (eg. HIV) and diabetes may prevent proper healing after a refractive procedure.
• Systemic medications likely to affect wound healing such as retinoic acid and steroids .
• Keratoconus or other active eye disease .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Alpins N. Astigmatism analysis by the Alpins method. J Cataract Refract Surg. 2001 Jan;27(1):31-49. doi: 10.1016/s0886-3350(00)00798-7.

  PMID: 11165856 BACKGROUND

MeSH Terms

Conditions

Astigmatism

Condition Hierarchy (Ancestors)

Refractive Errors; Eye Diseases

Study Officials

• Abdelnasser Awad, Professor

  Ophthalmology Department

  PRINCIPAL INVESTIGATOR

• Khaled Abdelazeem, Asst. Prof

  Ophthalmology Department

  PRINCIPAL INVESTIGATOR

• Mohamed Anwer, Lecturer

  Ophthalmology Department

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Esraa Fathy, Resident

CONTACT

01000323696; essraarateb94@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Ophthalmologist at Assiut Police Hospital

Study Record Dates

• First Submitted: May 25, 2021
• First Posted: June 4, 2021
• Study Start: July 1, 2021
• Primary Completion: July 1, 2022
• Study Completion: August 1, 2022
• Last Updated: June 4, 2021

Record last verified: 2021-05