Copy Number Variation in CHRNA7 Gene in Migraine and Gene Expression
Copy Number Variation in Migraine and Gene Expression
1 other identifier
interventional
200
1 country
1
Brief Summary
Migraine is a common and possible hereditary disease. Copy number variation (CNV) is a phenomenon in which parts of the genome are repeated and the number of repeats in the genome varies between individuals in the human population.The CHRNA7 gene has a major role in the neuropsychiatric phenotypes observed in patients. The 15q13.3 gain/loss variation in this gene may be associated with migraine.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Apr 2020
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 5, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 10, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
January 2, 2021
CompletedFirst Submitted
Initial submission to the registry
May 21, 2021
CompletedFirst Posted
Study publicly available on registry
June 3, 2021
CompletedJune 3, 2021
May 1, 2021
8 months
May 21, 2021
May 31, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
CNV number
CNV number effect on migraine
1 year
Study Arms (2)
Case-Control
OTHERCopy number variation
Case-Control 1
EXPERIMENTALGene expression
Interventions
Eligibility Criteria
You may qualify if:
- Migraine
You may not qualify if:
- Vascular problems
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Medicine
Gaziantep, Şehitkamil, 27310, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mehmet Fatih Özaltun, MD
Assist
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assoc. Prof.
Study Record Dates
First Submitted
May 21, 2021
First Posted
June 3, 2021
Study Start
April 5, 2020
Primary Completion
December 10, 2020
Study Completion
January 2, 2021
Last Updated
June 3, 2021
Record last verified: 2021-05
Data Sharing
- IPD Sharing
- Will not share
manuscript not yet published