NCT04912050

Brief Summary

Observational, retrospective and prospective, multicenter, post-market study of the Tablo Hemodialysis System in hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement therapy \> 12 hours.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 25, 2021

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

May 26, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 3, 2021

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2022

Completed
Last Updated

August 12, 2022

Status Verified

August 1, 2022

Enrollment Period

1 year

First QC Date

May 26, 2021

Last Update Submit

August 9, 2022

Conditions

Keywords

TabloOutset MedicalHemodialysisAKIESKD

Outcome Measures

Primary Outcomes (1)

  • Treatment Success

    Percentage of treatments achieving prescribed dialysis treatment time ≤ 10%

    Up to 24 hours

Secondary Outcomes (1)

  • Tablo Cartridge Life

    up to 24 hours

Study Arms (1)

Tablo Hemodialysis System

Hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement therapy \> 12 hours on the Tablo Hemodialysis System

Device: Tablo Hemodialysis System

Interventions

Renal Replacement Therapy between 12\< to ≤ 24 hours.

Tablo Hemodialysis System

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement therapy \> 12 hours.

You may qualify if:

  • Participant weighs ≥ 34kg.
  • Participant is hospitalized and has dialysis dependent End-Stage Kidney Disease or Acute Kidney Injury and is prescribed renal replacement therapy \> 12 hours.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Mark's Hospital

Salt Lake City, Utah, 84124, United States

Location

MeSH Terms

Conditions

Kidney Failure, ChronicAcute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 26, 2021

First Posted

June 3, 2021

Study Start

May 25, 2021

Primary Completion

May 31, 2022

Study Completion

May 31, 2022

Last Updated

August 12, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Only aggregated participant data is planned to be shared at this time.

Locations