NCT04901442

Brief Summary

To investigate whether a prefabricated Orthotic inserted into running shoes will increase comfort, decrease injury and improve speed during recreational running as compared to running shoes without the prefabricated Orthotic.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
106

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 14, 2021

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 25, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

July 23, 2021

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2022

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

October 21, 2022

Status Verified

October 1, 2022

Enrollment Period

1.1 years

First QC Date

May 14, 2021

Last Update Submit

October 20, 2022

Conditions

Outcome Measures

Primary Outcomes (3)

  • Changes in levels of comfort as assessed by a Visual Analogue Scale (VAS)

    Participants will record Comfort on a self-report Visual analogue scale (VAS) of 0 to 10 scale where 0 is "No comfort" and 10 is "Maximum comfort"

    Up to 8 weeks

  • Running Duration via a self report questionnaire

    Participants will record run duration in Hours:Minutes

    Up to 8 weeks

  • Running Distance via a self report questionnaire

    Participants will record run distance in Kilometres/Miles.

    Up to 8 weeks

Secondary Outcomes (1)

  • Running related Injuries

    Once a week during the 8-week trial period.

Study Arms (2)

Running with an Orthotic

ACTIVE COMPARATOR

Group A will receive an L700 Speed Orthotic (https://www.aetrex.com/running-orthotic/?lang=en\_US) according to participants shoe size and will run with this Orthotic in the participants normal running shoes. The investigators will send an instruction sheet along with the Orthotic in the post, explaining how to use it. Alternatively, an online video tutorial on how to use the Orthotic will also be available throughout the study. The group will be asked to run as normal over the 8-week trial period

Device: Aetrex L700 Speed orthotic

Running without an Orthotic

NO INTERVENTION

Group B will not be provided with the Orthotic and will run in the participants normal running shoes during the course of the study. The group will be asked to run as normal over the 8-week trial period. At the end of the study and following collection of data participants in Group B will also be provided with an L700 Speed Orthotic.

Interventions

An orthotic insole to be inserted into running shoes. Features Aetrex Arch Support to help biomechanically align the body \& help prevent common foot pain such as Plantar Fasciitis, Arch Pain, and Metatarsalgia. Helps prevent injury, alleviate discomfort and helps reduce fatigue while running

Running with an Orthotic

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18 years and over.
  • Used to running at least 5kms in the last 1 year.

You may not qualify if:

  • Are currently using a prescription orthotic.
  • Have any ongoing pain or deformity in the foot.
  • Have been advised by a doctor to not exercise due to a serious health condition.
  • Have undergone any surgery in the last 6 months.
  • Have undergone any surgery on the foot during lifetime.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Talita Cumi LTD.

Southport, Merseyside, PR8 3NS, United Kingdom

Location

Related Publications (12)

  • Collier R. Orthotics work in mysterious ways. CMAJ. 2011 Mar 8;183(4):416-7. doi: 10.1503/cmaj.109-3802. Epub 2011 Feb 14. No abstract available.

    PMID: 21324862BACKGROUND
  • Yamato TP, Saragiotto BT, Lopes AD. A consensus definition of running-related injury in recreational runners: a modified Delphi approach. J Orthop Sports Phys Ther. 2015 May;45(5):375-80. doi: 10.2519/jospt.2015.5741. Epub 2015 Mar 26.

    PMID: 25808527BACKGROUND
  • Lindorfer J, Kroll J, Schwameder H. Comfort assessment of running footwear: Does assessment type affect inter-session reliability? Eur J Sport Sci. 2019 Mar;19(2):177-185. doi: 10.1080/17461391.2018.1502358. Epub 2018 Jul 25.

    PMID: 30044208BACKGROUND
  • van Gent RN, Siem D, van Middelkoop M, van Os AG, Bierma-Zeinstra SM, Koes BW. Incidence and determinants of lower extremity running injuries in long distance runners: a systematic review. Br J Sports Med. 2007 Aug;41(8):469-80; discussion 480. doi: 10.1136/bjsm.2006.033548. Epub 2007 May 1.

  • Kemler E, Blokland D, Backx F, Huisstede B. Differences in injury risk and characteristics of injuries between novice and experienced runners over a 4-year period. Phys Sportsmed. 2018 Nov;46(4):485-491. doi: 10.1080/00913847.2018.1507410. Epub 2018 Aug 21.

  • Mundermann A, Stefanyshyn DJ, Nigg BM. Relationship between footwear comfort of shoe inserts and anthropometric and sensory factors. Med Sci Sports Exerc. 2001 Nov;33(11):1939-45. doi: 10.1097/00005768-200111000-00021.

  • Bonanno DR, Murley GS, Munteanu SE, Landorf KB, Menz HB. Effectiveness of foot orthoses for the prevention of lower limb overuse injuries in naval recruits: a randomised controlled trial. Br J Sports Med. 2018 Mar;52(5):298-302. doi: 10.1136/bjsports-2017-098273. Epub 2017 Oct 22.

  • Franklyn-Miller A, Wilson C, Bilzon J, McCrory P. Foot orthoses in the prevention of injury in initial military training: a randomized controlled trial. Am J Sports Med. 2011 Jan;39(1):30-7. doi: 10.1177/0363546510382852. Epub 2010 Nov 1.

  • van der Worp MP, ten Haaf DS, van Cingel R, de Wijer A, Nijhuis-van der Sanden MW, Staal JB. Injuries in runners; a systematic review on risk factors and sex differences. PLoS One. 2015 Feb 23;10(2):e0114937. doi: 10.1371/journal.pone.0114937. eCollection 2015.

  • Yeung SS, Yeung EW, Gillespie LD. Interventions for preventing lower limb soft-tissue running injuries. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001256. doi: 10.1002/14651858.CD001256.pub2.

  • Bonanno DR, Landorf KB, Munteanu SE, Murley GS, Menz HB. Effectiveness of foot orthoses and shock-absorbing insoles for the prevention of injury: a systematic review and meta-analysis. Br J Sports Med. 2017 Jan;51(2):86-96. doi: 10.1136/bjsports-2016-096671. Epub 2016 Dec 5.

  • Ampat, G., R. Baxter, and F. Geoghegan. Pedobarograph based prefabricated orthotics reduces self-reported minor injuries and improves comfort whilst running. MOJ Orthop Rheumatol 12.1 (2020): 1-5.

    RESULT

Related Links

Study Officials

  • George Ampat, MBBS, MS, FRCS

    Talita Cumi Ltd.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 14, 2021

First Posted

May 25, 2021

Study Start

July 23, 2021

Primary Completion

August 31, 2022

Study Completion

December 31, 2022

Last Updated

October 21, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will share

At the end of the study, data will be fully anonymised. Only non-identifiable, anonymised data will be archived along with the publication for use of other researchers. For instance, the age, sex, and study results of participants will be archived indefinitely as a supplementary document to the publication.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
Time Frame
The data will become available at the completion of the study on 31/12/2022. It will be available for other researchers indefinitely.
Access Criteria
The non-identifiable data will be openly available as a supplementary document to the publication.

Locations