Lacrimal Deroofing for Epiphora From Punctal Abnormalities

NCT04898933 | Completed

• 1 other identifier: Hamaky12
• Study Type: observational
• Target: 39
• Locations: 1 country
• Sites: 1

Brief Summary

Puncto-canalicular abnormalities, such as obstruction and canaliculitis, are a significant cause of epiphora. They involve proximal lacrimal drainage system. Proximal lacrimal obstructions classified into punctal stenosis canalicular obstructions. The basic principles in the treatment of punctal stenosis include creating an adequate opening, while maintaining the position of the punctum against the lacrimal lake, and preserving the lacrimal pump function. The severity of epiphora can be valued trough a grading system such as the Munk scale, fluorescein dye disappearance test, and syringing and probing and contrast dacryocystography. Canaliculitis is defined as infection of the proximal part of the lacrimal drainage system. This condition can be caused by primary infectious organisms or secondary to punctal plugs and lacrimal stents. Diagnosing canaliculitis is frequently misdiagnosed. The management includes conservative measures, local massage, syringing, and irrigation. Nevertheless, refractory cases required surgical intervention.

Conditions

Eyelid Diseases

Keywords

lacrimal; epiphora

Outcome Measures

Primary Outcomes (1)

• Munk scale for epiphora grading (0-5)

  0 No epiphora ,1 Epiphora requiring dabbing less than twice a day, 2 Epiphora requiring dabbing 2-4 times a day, 3 Epiphora requiring dabbing 5-10 times a day, 4 Epiphora requiring dabbing more than 10 times a day, 5 Constant epiphora.

  6 months

Interventions

lacrimal deroofing PROCEDURE

After infiltration anesthesia, patient underwent proximal lacrimal deroofing. Proper punctal dilatation is done, followed by combined 1 snip punctoplasty with a lateral canaliculotomy/ Punctotomy and posterior canaliculotomy of the lateral third. En-bloc expulsion of the concretion was done in case of canaliculitis.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

at least 18 years old patients

You may qualify if:

• epiphora due to lacrimal punctum stenosis and/or canaliculitis.

You may not qualify if:

• Trauma, Thyroid eye disease, lacrimation and other causes of epiphora.

Sponsors & Collaborators

• Benha University: lead

Study Sites (1)

INMC

Abu Dhabi, 46266, United Arab Emirates

Location

MeSH Terms

Conditions

Eyelid Diseases; Lacrimal Apparatus Diseases

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

• Tarek Elhamaky

  Benha University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: May 19, 2021
• First Posted: May 24, 2021
• Study Start: January 20, 2022
• Primary Completion: December 13, 2024
• Study Completion: January 23, 2025
• Last Updated: May 22, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: unlimited

Locations

AE (1)