Trials Sponsors Conditions Drugs Pricing

Conditions

Respiratory Failure (Pediatric Patients)

Outcome Measures

Primary Outcomes (1)

BPOI (Berlin Pediatric Oxygenation Index)
Evaluation of a certain cut-off value for the BPOI (Berlin Pediatric Oxygenation Index) that predicts imminent failure of high-flow nasal cannula (HFNC) therapy in paediatric patients.
01.01.2017-28.02.2021

Secondary Outcomes (7)

Heart rate
01.01.2017-28.02.2021
Respiratory rate
01.01.2017-28.02.2021
Blood pressure (mean arterial pressure, MAP)
01.01.2017-28.02.2021
Intensive care unit length of stay
01.01.2017-28.02.2021
High-flow nasal cannula therapy failure
01.01.2017-28.02.2021
+2 more secondary outcomes

Eligibility Criteria

Age28 Days - 17 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17)

Sampling MethodProbability Sample

Study Population

Pediatric Patients with respiratory failure and High-flow nasal cannula therapy (HFNC). Approximately 220 patients will be enrolled in the observational study. Their data collected during their entire hospital stay which is saved on the clinical data processing system will be evaluated to reproduce the BPOI (BPOI = (SpO2 \* kg) / (Flow \* FiO2) ) We will compare the indices of patients who failed and those who were successfully treated with HFNC therapy. Failure is defined by the need for non-invasive or invasive mechanical ventilation.

You may qualify if:

Sponsors & Collaborators

Charite University, Berlin, Germany
Otherlead

MeSH Terms

Conditions

Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract Diseases

Study Officials

Claudia Spies, MD, Prof.
Charite University, Berlin, Germany
STUDY DIRECTOR

Enrollment

0 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Department of Anesthesiology and Operative Intensive Care Medicine (CCM/CVK)

Study Record Dates

First Submitted

May 17, 2021

First Posted

May 20, 2021

Study Start

June 21, 2021

Actual (reported)

Study Stopped

BPOI (Berlin Pediatric Oxygenation Index) - A New Predictor for Imminent Failure of HFNC in Children Avoiding Delayed NIV or Intubation

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (7)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (7)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record