The Effect of Overtime Pancreaticoduodenectomy on the Short-term Prognosis of Patients(EOPSPP)

NCT04881734 | Completed DMC

• 1 other identifier: 2021PHB050-001
• Study Type: observational
• Target: 235
• Locations: 1 country
• Sites: 1

Brief Summary

Surgeons sometimes need to work overtime or even stay up late to perform pancreaticoduodenectomy. Fatigue and sleep deprivation can result in an increased error rate at work. The effect of overtime work for pancreaticoduodenectomy on the prognosis of patients is unclear. The study explores the impact of overtime work for pancreaticoduodenectomy on the prognosis of patients. This was a single-center, retrospective study. The patients who underwent pancreaticoduodenectomy in Peking University People's Hospital between 2017 and 2019 were included. Patients were stratified by operative start time into the control group (surgery that started between 8:00 and 16:49) and the overtime group (surgery that started between 17:00 and 22:00) and compared intraoperative and postoperative parameters to clarify the impact of overtime surgery on the short-term prognosis of patients.

Conditions

Pancreaticoduodenectomy; Fatigue

Keywords

Pancreaticoduodenectomy; Overtime surgery; Fatigue; Outcomes

Outcome Measures

Primary Outcomes (2)

• Operative time

  The time elapsed from the patient's opening to closing the abdomen

  Intraoperative

• Postoperative complication rate

  Postoperative complications include pancreatic fistula, gastric emptying disorder, abdominal cavity infection, and non-surgical-related complications.

  1 year

Secondary Outcomes (1)

• Blood loss

  Intraoperative

Study Arms (2)

the control group and the overtime group

Patients who started surgery between 8:00 and 16:59 were included in the control group.

Other: Overtime pancreaticoduodenectomy

the overtime group

Patients who started surgery from 17:00 to 22:00 were included in the overtime group.

Other: Overtime pancreaticoduodenectomy

Interventions

Overtime pancreaticoduodenectomy OTHER

Compared with daytime surgery, the intervention in this study is to work overtime after 17:00 to perform pancreaticoduodenectomy.

the control group and the overtime group; the overtime group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who underwent pancreaticoduodenectomy at the Department of Hepatobiliary Surgery, Peking University People's Hospital from January 2017 to December 2019

You may qualify if:

• patients who underwent pancreaticoduodenectomy at the Department of Hepatobiliary Surgery, Peking University People's Hospital from January 2017 to December 2019

You may not qualify if:

• Patients with missing clinical data were excluded.

Sponsors & Collaborators

• Peking University People's Hospital: lead

Study Sites (1)

Peking University People's Hospital

Beijing, 100044, China

Location

Related Publications (8)

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  PMID: 10329298 BACKGROUND

• Mu Q, Mishory A, Johnson KA, Nahas Z, Kozel FA, Yamanaka K, Bohning DE, George MS. Decreased brain activation during a working memory task at rested baseline is associated with vulnerability to sleep deprivation. Sleep. 2005 Apr;28(4):433-46. doi: 10.1093/sleep/28.4.433.

  PMID: 16171288 BACKGROUND

• Folkard S, Lombardi DA. Modeling the impact of the components of long work hours on injuries and "accidents". Am J Ind Med. 2006 Nov;49(11):953-63. doi: 10.1002/ajim.20307.

  PMID: 16570251 BACKGROUND

• Bosca A, Montalva EM, Maupoey J, Arguelles B, Navio A, Calatayud D, Camacho A, Garcia-Eliz M, Lopez-Andujar R. Does Surgeon Fatigue Influence the Results of Liver Transplantation? Transplant Proc. 2019 Jan-Feb;51(1):67-70. doi: 10.1016/j.transproceed.2018.03.139. Epub 2019 Jan 2.

  PMID: 30611547 BACKGROUND

• Brunschot DM, Hoitsma AJ, van der Jagt MF, d'Ancona FC, Donders RA, van Laarhoven CJ, Hilbrands LB, Warle MC. Nighttime kidney transplantation is associated with less pure technical graft failure. World J Urol. 2016 Jul;34(7):955-61. doi: 10.1007/s00345-015-1679-0. Epub 2015 Sep 14.

  PMID: 26369548 BACKGROUND

• McEvoy SH, Lavelle LP, Hoare SM, O'Neill AC, Awan FN, Malone DE, Ryan ER, McCann JW, Heffernan EJ. Pancreaticoduodenectomy: expected post-operative anatomy and complications. Br J Radiol. 2014 Sep;87(1041):20140050. doi: 10.1259/bjr.20140050. Epub 2014 Jul 16.

  PMID: 25026968 BACKGROUND

• Warshaw AL, Thayer SP. Pancreaticoduodenectomy. J Gastrointest Surg. 2004 Sep-Oct;8(6):733-41. doi: 10.1016/j.gassur.2004.03.005. No abstract available.

  PMID: 15358336 BACKGROUND

• Cameron JL, Riall TS, Coleman J, Belcher KA. One thousand consecutive pancreaticoduodenectomies. Ann Surg. 2006 Jul;244(1):10-5. doi: 10.1097/01.sla.0000217673.04165.ea.

  PMID: 16794383 BACKGROUND

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Dafang Zhang, PhD

  Peking University People's Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Associate Professor

Study Record Dates

• First Submitted: May 6, 2021
• First Posted: May 11, 2021
• Study Start: January 1, 2021
• Primary Completion: April 10, 2021
• Study Completion: April 29, 2021
• Last Updated: May 12, 2021

Record last verified: 2021-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)