NCT04879927

Brief Summary

The purpose of this research is to understand how screening for patient resource needs followed by customized resource matching can improve outcomes for adults with breast, lung or gastrointestinal cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
125

participants targeted

Target at P50-P75 for not_applicable breast-cancer

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 5, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 10, 2021

Completed
7 days until next milestone

Study Start

First participant enrolled

May 17, 2021

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2023

Completed
Last Updated

May 3, 2023

Status Verified

May 1, 2023

Enrollment Period

1.4 years

First QC Date

May 5, 2021

Last Update Submit

May 1, 2023

Conditions

Keywords

Breast CancerLung CancerGastrointestinal Cancer

Outcome Measures

Primary Outcomes (6)

  • Number of Patients Treatment Interruption

    Number of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    30 Days

  • Number of Patients Treatment Interruption

    Number of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    90 Days

  • Number of Patients Treatment Interruption

    Number of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    180 Days

  • Rate of Treatment Interruption

    Rate of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    00 Days

  • Rate of Treatment Interruption

    Rate of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    90 Days

  • Rate of Treatment Interruption

    Rate of interruptions to cancer treatment (defined here as treatment hold, reduction, discontinuation or ED visits/hospitalizations as indicated by the patient medical record)

    180 Days

Study Arms (2)

RESOURCE Matching

EXPERIMENTAL

Participants randomized into the intervention arm will receive customized resource matching

Other: Resource Matching

Usual Care

ACTIVE COMPARATOR

Participants randomized into the control group will receive a pre-existing pamphlet detailing DFCI resources

Other: Usual Care

Interventions

Resource staff involved in the customized resource matching arm of the intervention will include staff from DFCI Patient Services and DFCI Financial Counseling. Financial counseling will support patients with financial resource needs. DFCI Patient Services will provide assistance for all other patient Social Determinants of Health needs.

RESOURCE Matching

Patients randomized to the control group will receive a pre-existing pamphlet detailing DFCI resources.

Usual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Eligible patients will be adults age 18 or older, able to consent, scheduled for a new patient consultation in DFCI BOC, TOP or GCC. To select for patients from demographic groups vulnerable to SDoH needs, two different groups will be eligible to participate.
  • Group A
  • BIPOC (Black, Latinx, Native American or Pacific Islander)
  • LEP Spanish-speaking (As indicated by the EHR)
  • Low SES (from zip code with median household income \<$32,000/year) OR
  • Age 70+
  • Group B
  • Any one NPIQ response indicating SDoH need
  • Health literacy/numeracy, Caregiving/relationships, OR Finances

You may not qualify if:

  • \- Group A and B
  • \-- Patients not continuing care at Dana Farber Cancer Institute

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dana Farber Cancer Institute

Boston, Massachusetts, 02215, United States

Location

MeSH Terms

Conditions

Breast NeoplasmsLung NeoplasmsGastrointestinal Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue DiseasesRespiratory Tract NeoplasmsThoracic NeoplasmsLung DiseasesRespiratory Tract DiseasesDigestive System NeoplasmsDigestive System DiseasesGastrointestinal Diseases

Study Officials

  • Nadine J. McCleary, MD, MPH

    Dana-Farber Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 5, 2021

First Posted

May 10, 2021

Study Start

May 17, 2021

Primary Completion

October 1, 2022

Study Completion

April 1, 2023

Last Updated

May 3, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will share

The Dana-Farber / Harvard Cancer Center encourages and supports the responsible and ethical sharing of data from clinical trials. De-identified participant data from the final research dataset used in the published manuscript may only be shared under the terms of a Data Use Agreement. Requests may be directed to Sponsor Investigator or designee. The protocol and statistical analysis plan will be made available on Clinicaltrials.gov only as required by federal regulation or as a condition of awards and agreements supporting the research.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data can be shared no earlier than 1 year following the date of publication
Access Criteria
DFCI - Contact the Belfer Office for Dana-Farber Innovations (BODFI) at innovation@dfci.harvard.edu

Locations