Retrospective Study of Intracerebral Hemorrhage Patients in Hospital Parc Taulí
Retrospective Study to Identify Correlations Between the Clinical Parameters, Analytics and Neuroimaging Data in Patients That Suffered of Intraparenchymal Cerebral Hemorrhage
1 other identifier
observational
137
1 country
1
Brief Summary
This is a retrospective observational study to investigate the clinical, analytical and neuroimaging data generated during routine clinical management of intracerebral hemorrhage. The study will review the data from about 500 patients attended during the last ten years in the Neurology Department of Hospital Parc Taulí de Sabadell. The aim is to measure the size of the lesion in neuroimage (TC and MRI), the edema, the alterations in diffusion weighted images and to correlate this data with clinical parameters and analytical measurements. With this approach investigators plan to investigate the incidence of hematoma growth, the role of perilesional edema and diffusion changes, and the relation between neuroimaging findings and clinical outcome. The study also try to establish significant correlations between clinical and analytical data, the clinical outcome and and the magnitude of changes in neuroimaging.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 29, 2021
CompletedFirst Posted
Study publicly available on registry
May 7, 2021
CompletedStudy Start
First participant enrolled
May 10, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2022
CompletedMay 26, 2022
May 1, 2022
11 months
April 29, 2021
May 19, 2022
Conditions
Outcome Measures
Primary Outcomes (14)
Hematoma growth
Difference of hematoma size between CT conducted at admission and MRI conducted during follow up
2 days
Correlation between hematoma growth and clinical paramenters
Determine the clinical parameters related with hematoma growth
2 days
Correlation between hematoma growth and analytical parameters
Determine the analytical parameters related with hematoma growth
2 days
Perilesional edema
Size of edema measured in FLAIR sequences
2 days
Correlation between clinical parameters and the size of edema measured in FLAIR sequences
Determine the relationship between clinical parameters and the size of edema
2 days
Correlation between analytical parameters and the size of edema measured in FLAIR sequences
Determine the relationship between analytical parameters and the size of edema
2 days
Alterations in DWI
Size of alterations in diffusion weighted image
2 days
Correlation between clinical parameters and the size of alterations in DWI
Determine the relationship between clinical parameters and the size of alterations in DWI
2 days
Correlation between analytical parameters and the size of alterations in DWI
Determine the relationship between analytical parameters and the size of alterations in DWI
2 days
Correlation between hematoma growth and clinical outcome
Determine the impact of hematoma growth on clinical outcome
1 month
Correlation between perilesional edema size and clinical outcome
Determine the relationship between the size of edema and clinical outcome
1 month
Correlation between the size of DWI alterations and clinical outcome
Determine the relationship between the size of DWI alterations and clinical outcome
1 month
Correlation between the clinical parameters and clinical outcome
Determine the relationship between the clinical parametes and clinical outcome
1 month
Correlation between the analyticial parameters and clinical outcome
Determine the relationship between the analytical parametes and clinical outcome
1 month
Study Arms (1)
Intracerebral hemorraghe
Patients that suffered an intracerebral hemorraghe and that have been subjected to CT and MRI scans
Interventions
This observational study is not focused on therapeutic intervention
Eligibility Criteria
The study population consist in the patients attended due to spontaneous intracerebral hemorrhage in Hospital Parc Taulí de Sabadell during the last decade. Traumatic or oncologic origin of the hemorrhage constitute exclusion criteria of the study.
You may qualify if:
- Patients who have been attended at the Hospital Parc Taulí for the last 10 years after presenting an intraparenchymal hemorrhage.
- The patients have had to undergo a computed tomography at the admission and a cranial magnetic resonance during the hospitalization in the time course specified in point in the protocol
- The patients must present in their clinical story the analytical determinations detailed in the protocol.
You may not qualify if:
- Intracerebral hemorrhage secondary to head trauma
- Intracerebral hemorrhage secondary to neoplasm
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Santiago Rojas Codina MD PhD
Cerdanyola del Vallès, Barcelona, 08193, Spain
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
April 29, 2021
First Posted
May 7, 2021
Study Start
May 10, 2021
Primary Completion
March 31, 2022
Study Completion
March 31, 2022
Last Updated
May 26, 2022
Record last verified: 2022-05