NCT04869501

Brief Summary

This expanded access protocol was designed to provide TJ004309 in combination with atezolizumab to the remaining three patients with advanced or metastatic cancer who plan to continue with treatment.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 3, 2021

Completed
Last Updated

April 28, 2023

Status Verified

April 1, 2023

First QC Date

April 28, 2021

Last Update Submit

April 27, 2023

Conditions

Interventions

Antibody to CD73

Humanized monoclonal antibody to PD-L1

Also known as: Tecentriq

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Participation in the Tracon sponsored 4309ST101 or I-Mab sponsored TJ004309STM103 study and thought to have potential to derive clinical benefit from continued treatment in the opinion of the parent study investigator from dosing of TJ004309 in combination with atezolizumab.
  • Willing or able to comply with study treatment and standard of care testing and procedures.

You may not qualify if:

  • Any unresolved ongoing toxicity or clinical event that would make continued treatment with TJ004309 inappropriate.
  • Current treatment in another clinical study or treatment with other standard of care therapy.
  • Currently pregnant.
  • Current evidence of any condition (including medical, psychiatric or substance abuse disorder), therapy, or laboratory abnormality that might interfere with the patient's participation or is not in the best interest of the patient to participate, in the opinion of the treating Investigator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States

Location

HonorHealth Research Institute

Scottsdale, Arizona, 85258, United States

Location

Arizona Oncology Associates, P.C.

Tucson, Arizona, 85704, United States

Location

MeSH Terms

Conditions

Neoplasms

Interventions

atezolizumab

Study Design

Study Type
expanded access
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2021

First Posted

May 3, 2021

Last Updated

April 28, 2023

Record last verified: 2023-04

Locations